lauren chin

Conducted an indirect treatment comparison to evaluate the relative efficacy of insulin glargine/lixisenatide (SOLIQUA) versus insulin degludec/liraglutide (XULTOPHY) in the absence of head-to-head trials to inform internal discussions Prepared a monograph to assess formulary placement of insulin glargine/lixisenatide for the treatment of type II diabetes mellitus on behalf of Premera Blue Cross

▪ Economic model: Developed an economic model to estimate the economically justifiable price of a novel intervention for use internally as part of a business plan. Assessed literature and gathered data to develop two decision trees to assess and compare costs between treatment decisions and conducted two-way sensitivity analyses ▪ Targeted literature review: Conducted a targeted literature review and developed a research protocol for internal use ▪ Patient-reported outcome (PRO) literature review: Postmenopausal hypoactive sexual desire disorder (HSDD). Systematically reviewed all PROs intended for use in HSDD populations using PROQOLID/PROLABELS, PubMed, ClinicalTrials.gov, FDA/EMA drug labels. Reviewed development and validation histories for PROs ▪ Clinician-reported outcome (ClinRO) report: Prepared a report regarding the Desirability of Outcome Ranking (DOOR)/Response Adjusted for Duration of Antibiotic Risk (RADAR) ClinRO instrument to support internal discussions

Prepared a monograph to assess formulary placement of telotristat ethyl (XERMELO) for the treatment of carcinoid syndrome diarrhea on behalf of Premera Blue Cross

* Novel catalyst and ligand synthesis involving organometallic compounds (palladium) * Run synthesized compounds through NMR spectrometers (Varian Mercury 400 NMR Spectrometer)

* Identification of novel tumor suppressor genes, oncogenes, and cell cycle regulatory genes in planarian model system * Help manage laboratory fly stock lines

* Receive and process written, electronic, and faxed prescriptions * Transcribe new prescriptions and transfers via telephone * Dispense medications via Kirby Lester KL100 and KL1Plus Robotics * Receive and process inter-chain prescription drug transfers * Process insurance claims * Provide counseling for patients on proper medication use (legend and OTC drugs) * Administer influenza (IM/intranasal), TDap, Adacel, Prevnar, Pneumovax, and Zostavax vaccines to patients

Activities and Societies: Undergraduate Research: Dr. Kyung Jung - Loker Hydrocarbon Research Instititute, Dr. Sergey Nuzhdin - Nuzhdin Laboratory. Undergraduate Student Government (USG) Academic Research & Professional Funding Committee, Chinese American Student Association, Trojan Health Connection

Research Assistant - Dr. Beth Devine (February 2015 - Present) * Firsthand experience in conducting an indirect treatment comparison via hand-calculated hazard ratios for overall survival and progression-free survival * Conducted a systematic literature review and network meta-analysis in the frequentist approach using R and Stata * Developed and submitted a manuscript for publication Academic Research Projects * Comparative Effectiveness of Marketed Agents Used for the Treatment of Pulmonary Arterial Hypertension: A Systematic Literature Review and Network Meta-Analysis * Clinical Evidence Supporting Pharmacogenomic Biomarker Testing Provided in US Food and Drug Administration Drug Labels: An Update * Leveraging a Clinical Data Repository to Characterize the Landscape of Pharmacogenomic Biomarker-Guided Medication Use * Indirect Treatment Comparison of Agents Used for the Treatment of BRAF-negative and BRAF-positive Metastatic Melanoma Activities and Societies: UW AMCP