Lívia Palmerston Mendes

Senior Scientist @ NanoVation Therapeutics™

About

Research experience spanning over 15 years, working mostly with the development of lipid and polymeric nanoparticles for the delivery of anti-cancer drugs and gene delivery systems. I work to modify and optimize formulations and assays to meet specific parameters. My background allowed me to acquire extensive formulation experience and great fluency of nanoparticle characterization techniques, including dynamic light scattering, zeta potential, nanoparticle tracking analysis, and in vitro drug release, analytical methods, cell-based assays and in vivo mouse models. Strong critical thinking, problem-solving, and project management skills, besides leadership experiences managing small groups of research assistants and technicians. I have always been driven by challenge, curiosity, and a desire to learn.

Country

Canada

City

Vancouver

Industry

Biotechnology

Skill

Cross-functional Collaborations, Communication, Vaccines, Immunofluorescence, Cross-team Collaboration, Gene Therapy, Quality Control, Pharmaceutical industry, Pharmaceutical Sciences, Leadership, Laboratory Skills, Lipid nanoparticles, Teamwork, Biotechnology, Drug Delivery, R&D, Cell Culture, Nanotechnology, Pharmaceutics, ELISA

Experience

Senior Scientist

NanoVation Therapeutics™

2024-3 - Present · 2 yrs 7 mos

Ванкувер, BC

Senior Scientist

CureVac

2022-4 - 2024-2 · 1 yr 11 mos

Tübingen, Baden-Württemberg, Germany

Formulation Scientist

CureVac

2020-2 - 2022-4 · 2 yrs 3 mos

Tübingen, Baden-Württemberg, Germany

Postdoctoral Research Associate

Northeastern University

2018-8 - 2020-1 · 1 yr 6 mos

Greater Boston Area

- Development of lipid- and polymer-based nanomedicine for antibiotic delivery in collaboration with the Antimicrobial Discovery Center at Northeastern University. - Design lipid nanoparticles and polymer-based nanocomplexes (e.g. LNPs, liposomes, micelles) for drug and oligonucleotide delivery against cancer cells. - Development of in vitro model to investigate neutrophil extracellular traps (NETs). - Oversee different projects within the laboratory, including outside collaborations. - Managing a small group of researchers with different backgrounds and levels of experience.

Ph.D. Candidate

Northeastern University

2014-9 - 2018-7 · 3 yrs 11 mos

Grande Boston e Região, Estados Unidos

- Development and characterization of liposomes and micelles for water insoluble drugs and gene delivery for cancer therapy. - Worked on synthesis of stimuli-sensitive polymers and other polymer/lipid conjugates. - Performed in vitro studies in monolayers and 3-D cell culture models. - Performed in vivo assays to evaluate the anti-tumor efficacy of liposomes co-delivering small molecule and siRNA in xenograft tumor-bearing mice.

Graduate Research Assistant

Universidade Federal de Goiás

2012-10 - 2014-6 · 1 yr 9 mos

Laboratory of Nanotechnology and Drug Delivery Systems, Goiania, Brazil

- Fellowship in research, development and innovation funded by the Brazilian National Council for Scientific and Technological Development - Developed multifunctional nanosystems to achieve controlled delivery properties of the encapsulated bioactive compounds and improve skin permeation

Master Thesis Student

Universidade Federal de Goiás

2010-9 - 2012-9 · 2 yrs 1 mo

Laboratory of Nanotechnology and Drug Delivery Systems, Goiania, Brazil

- Development of multicompartmental nanoparticles for simultaneous encapsulation of a cytotoxic drug and an antiangiogenic and chemoprotector agent to improve antitumor efficacy by synergism of both drugs.

Research Assistant

Universidade Federal de Goiás

2007-8 - 2010-8 · 3 yrs 1 mo

Laboratory of Nanotechnology and Drug Delivery Systems, Goiania, Brazil

- Development and physical-chemical characterization of liposomes and polymeric nanoparticles, especially for the entrapment of antitumor drugs

Quality Control Analyst

Cifarma Científica Farmacêutica LTDA.

2009-12 - 2010-7 · 8 mos

BR-153, 5 - Jardim Guanabara, Goiânia - GO, Brasil

Responsible for physical-chemical analysis of raw materials, bulk intermediate, and finished products by HPLC, UPLC, UV-Vis spectroscopy and titration; preparation and standardization of reagents; dissolution assays