Lim Gaik Ling

Promoted for exceeding KPIs and delivering strategic contributions Key accomplishment: Successfully incorporated lateral flow immunoassays into a lateral flow reader and achieved 95-100% of agreement in performance. Roles and responsibilities: -Lead the development of fluorescence POCT with reader integration -Expand and optimise manufacturing capabilities to include contract manufacturing services -Manage the full product lifecycle of lateral flow immunoassays, from R&D to commercial production -Drive the manufacturing scale up, increasing production throughput and efficiency -Facilitate seamless technology transfer between R&D and production teams -Oversee quality data analysis, driving continuous process improvements for product consistency and reliability -Design and execute validation protocols for equipment, reader systems, processes, and test methods -Author and review technical documentation, including SOPs, reports, protocols, ensuring alignment with regulatory requirements -Increased upstream production capacity, optimising workflow efficiency and scalability -Conducted gap analyses, identifying technical challenges, and implementing preventive actions for technical transfer and production scaling -Oversee project management, ensuring timely completion of milestones aligned with organisational objectives

Key accomplishments: - Established lateral flow immunoassays development platform for the initiation of projects -Successfully converted two ELISA test kits into lateral flow immunoassays with more than 95% agreement in performance - Successfully completed the development of three lateral flow immunoassays - Up-scaled protein conjugation production to 20x Roles and responsibilities: - Properly grounded the research and development of new lateral flow immunoassays, with a primary emphasis on infectious diseases - Led the seamless transfer of prototypes/products from the lab bench to commercialisation - Continuously enhanced the R&D platform for lateral flow immunoassays - Established and refined manufacturing processes for lateral flow immunoassays, prioritising on scalability, efficiency, and quality control - Collaborated with cross-functional teams and external institutions, including manufacturing, quality assurance, and regulatory affairs, to facilitate the smooth transfer of products and align with organisational goals; and universities and organisations on collaborative R&D of IVD projects - Mentored and trained individuals in lateral flow immunoassays development and manufacturing

Key accomplishments: - Resolved complex and longstanding troubleshooting cases, resulting in successful of brand switching from competitors and customers retention - Spearheaded and initiated the establishment of SOPs for the applications team, streamlining processes and ensuring consistent and high-quality performance - Actively mentored and guided applications specialists and sales team, enhancing their expertise in troubleshooting, after-sales service, and customer support - Provided comprehensive training to healthcare professionals by conducting on- and off-site technical troubleshooting, empowering healthcare professionals to perform tests with accuracy and realibility - Engaged in collaborative efforts with professionals from various disciplines, seeking insights and feedback to enhance the performance and usability of marketed IVD test kits

Key accomplishments: - Assumed responsibility for the development of a non-invasive genomic signature panel for multi-disease prediction using microarray-based mRNA analysis, steering the project from its midway state to completion with improved performance to 90-95%, enabling the marketability of the panel Roles and responsibilities: - Oversaw and managed the diagnostic service for RT-qPCR tests used in the prediction of colorectal and prostate cancers. Ensured the seamless operation of the service, guaranteeing prompt and reliable test results for patients by adhering to SOPs and quality control standards set by the US counterpart - Played a proactive role in the accreditation process for ISO 15189, contributing to the development and implementation of required QMS. Collaborated with internal teams and external auditors to ensure successful accreditation

Key Accomplishments - Completed four bioassay screening projects with two projects with a pharmaceutical company and two with universities • Published the biofilm study in a journal paper Roles and Responsibilities - Spearheaded the development and implementation of the microbial biofilm culture platform, enabling the execution of biofilm-related studies. Developed robust protocols and procedures to ensure consistency and reliability in the results obtained from the platform. Leveraging expertise in microbiology to optimise conditions for biofilm growth and evaluation - Established SOPs for bioassay screening, ensuring uniformity and reproducibility in evaluating the antimicrobial and antibiofilm activities and substances against hospital-acquired pathogens - Established and facilitated collaborative partnerships with pharmaceutical companies and universities to foster joint initiatives, shared resources, expertise, and data in bioassay screening projects

Roles and Responsibilities: - Successfully completed GMP (Good Manufacturing Practices) internal training and performed routine microbiological testing and analysis of various samples, including raw materials, in-process samples, finished products, and environmental monitoring. Ensured adherence to regulatory standards and comply specifications, verifying the safety and quality of products - Supported the identification of root causes and implementation of corrective actions to maintain product quality and regulatory compliance. Maintained accurate documentation and records of quality control activities - Reviewed and provided recommendations for improvements and updates to SOPs related to microbiological testing and quality control processes

- Conducted independent research on the study of different PhaCCn variants generated through site-directed mutagenesis on the production of bioplastics (PHA) by a bacterial host with the usage of different plasmids - Presented research work at local and international conferences - Assisted numerous practical classes in USM related to Biochemistry, Genetics and Biotechnology