
L M
R&D Chemist I with PPG Automotive Adhesives and Sealants Group @ PPG
About
My research is focused on using polymer science and nanotechnology to create novel biocompatible nanoparticle-based sensors and drug delivery vehicles, and to use these materials for cancer diagnosis and treatment of obesity-induced insulin resistance. In my research, I study the chemistry and physics of the interface between multidentate polymeric ligands and quantum dots (QDs) core, synthesize polysaccharide nanocarriers for bioimaging and drug delivery, design new chemistry for developing novel stimuli-responsive polymers, and evaluate the nanotoxicity of QDs on cells and tissues.
China
Anhui
Chemicals
GPC, HPLC, FI-TR, UV/Vis, TGA, DSC, DLS, SEM, TEM, CV, Fluorescence Spectroscopy, Contact Angle, NMR, Scanning Electron Microscopy, FTIR, Polymer Chemistry, Powder X-ray Diffraction, Characterization, Nanotechnology, Materials Science
Experience

Research Assistant
University of Illinois at Urbana-Champaign
Urbana-Champaign, Illinois Area
Conducted 106 customer interviews to build our business model canvas as the Entrepreneurial Lead in 2017 NSF I-Corps Program (2017 summer) Further optimized multidentate polymeric ligand structure for size minimization and reducing nonspecific binding of QDs

Research Assistant/IETP Toxicology Scholar
Micro and Nanotechnology Laboratory
Surface Engineering of Quantum dots (QDs) for Multiplexed Bioimaging Synthesized core/shell semiconductor QDs Synthesized multidentate polymers for QDs water solubilization Creatively developed a novel coating process for making compact and homogeneous QDs Engineered water soluble QDs that outperform commercial QDs in terms of size, stability and nonspecific binding Optimized the staining methods for QDs based immunofluorescence protocol Preventative Treatment of Obesity-induced Insulin Resistance Using Polysaccharide Nanocarriers Synthesized a series of dextran conjugates for bioimaging and drug delivery Studied the in vitro drug release profile of dextran drug conjugates Demonstrated a novel targeted delivery strategy to ameliorate obesity associated inflammation Developing Nontoxic QDs Modified QDs surface with different coatings Evaluated the in vitro cytotoxicity of QDs on cells and antral follicles Demonstrated a unique cytotoxic mechanism of cadmium-free ZnSe QDs

Research Assistant
Materials Science and Engineering Building
Degradable Polymeric Nanoparticles for Controlled Release Designed a novel self-immolative linker and studied its degradation kinetics Synthesized photo-responsive degradable polyesters and polyurethanes based on the self-immolative linkers Formulated polymeric nanoparticles through the emulsion method Demonstrated a burst release profile of the payload upon exposure of nanoparticles to UV light
L M's Contact Information
Phone
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