Li Yi
Director of Protein Engineering @ Summit Therapeutics, Inc.
About
-Focus on protein science, expertise spanning conventional antibody discovery and enzyme engineering and advanced technologies, -HTP/Automation platforms combined with computational biology for therapeutics (minibinder, VHH, antibody and enzyme) engineering, -AI/ML in therapeutic and synthetic biological research, especially on HTP data acquisition, de novo design, -Multi-specific antibody engineering and drug development, -New tech innovation and evaluation,
United States
Menlo Park
Pharmaceuticals
-
Experience
Director of Protein Engineering
Summit Therapeutics, Inc.
• Antibody engineering, • Drug development.
Director of Protein Design and Engineering
BioMap
Menlo Park, California, United States
• Lead cross-functional teams partnering with computational scientists for next-generation therapeutic development (antibody, VHH, mini-binder, enzyme) for various diseases (BBB, LSD, autoimmune, oncology), ML/AI model development, and de novo protein design pipelines optimization, • HTP platform development for drug screening and and AI/ML biological data acquisition, • Data-driven, wet-dry close loop-guided next generation drug development, • Oversee U.S. site operations and partner with executive leadership to shape research direction and strategic planning.
Team Leader/Principal Scientist/Senior Scientist
Novo Nordisk
• Led high-throughput protein drug screening and data acquisition at the Seattle Center, focusing on CADD collaboration, library design, surface display, and HTP assay development, • Promoted global collaborations (Novo Nordisk research centers, academia, industry) in de novo drug design, nanobody/antibody ML modeling, AAV gene therapy, and automation platform development, • Oversaw reporting, mentor scientists, and contribute to publications and patents.
Research Scientist
Clayton Foundation For RES
Austin, Texas Area
Professor
Hubei University
• Directed innovative research in antibody/protein/enzyme engineering, HTP protein-protein interaction, microbial cell factories, Crispr-based genome editing, • Contributed professional services through conference organization, review panels, editor roles, and faculty recruitment.
Research Fellow/Research Associate/Post-doc Research Fellow
The University of Texas at Austin
Austin, Texas Area
Dr. Brent Iverson’s and Dr. George Georgiou’s research groups, focused on developing FACS-NGS based HTP protein engineering technologies for therapeutics engineering
Education
University of Michigan Medical School
University of Nebraska-Lincoln
Li Yi's Contact Information
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