Leon Xu

Director of CMC @ ModeX Therapeutics Inc

About

Experienced as an industrial leader with over 20 years of biotech and pharmaceutical experience, specialized in protein purification and process development for products from early stage to late stage. Seasoned in process development, process optimization, process characterization, tech transfer, and GMP manufacturing support. Led various groups as a leader in both direct and matrix management roles to achieve multiple project goals on time and under budget. Demonstrate a track record of delivering innovative solutions.

Country

United States

City

Bloomington

Industry

Biotechnology

Skill

Assay Development, Protein Chemistry, Biotechnology, Antibodies, Purification, Drug Discovery, Process development, Contract Manufacturing, Life Sciences

Experience

Director of CMC

ModeX Therapeutics Inc

2022-10 - Present · 4 yrs

Director

Allakos Inc

2021-11 - 2022-9 · 11 mos

Downstream Process Development from lab scale, pilot scale and GMP manufacturing scale

Principle Scientist

Eli Lilly and Elanco

2016-10 - 2021 · 4 yrs

Indianapolis, Indiana Area

Biopharmaceutical API Development

Biotech Professional

Cook Pharmica

2011 - 2016-10 · 5 yrs

Bloomington, Indiana Area

Protein Purification/Process Development

Senior Scientist

FibroGen, Inc.

2000 - 2011 · 11 yrs

Protein Purification/Process Development/etc

Scientist

Scios

1998 - 2000 · 2 yrs

• Involved in development of VEGF-121 (vascular endothelial growth factor) manufacturing process prototype and solved two critical technical steps: optimization of the refolding process by utilizing factorial design screening and removal of extra amino acid residues by enzymatic cleavage. • Involved in the process development for BNP (Natrecor®). • Developed many in-process assays and analytical assays in support of product development.