Sandeep Kumar
Sr. Director, Biologics and CMC @ DEM Biopharma, Inc.
About
Experienced leader in Biologics drug development with 10+ years of experience in establishing Antibody Discovery, Engineering, and Display platforms and building and managing research teams. Research focus: Protein engineering, phage display, yeast display, NGS, kinetics, molecular modeling, and structure-activity relationships.
United States
Cambridge
Biotechnology
Biochemistry, Molecular Biology, Molecular Modeling, Molecular Dynamics, Quantum Chemistry, Computational Chemistry, Bioinformatics, Enzyme Kinetics, Enzyme Assays, Stopped-flow fluorescence spectroscopy, Immunoassays, ELISA, Mutagenesis, Flow Cytometry, Phage Display, Yeast Display, Protein Engineering, Molecular Cloning, Protein Purification, NMR
Experience
Sr. Director, Biologics and CMC
DEM Biopharma, Inc.
Cambridge, Massachusetts, United States
Director, Antibody Discovery & Development
DEM Biopharma, Inc.
Cambridge, Massachusetts, United States
Director, Antibody Discovery & Engineering
Scholar Rock
Cambridge, Massachusetts, United States
Associate Director, Antibody Discovery & Engineering
Scholar Rock
Cambridge, Massachusetts, United States
Principal Scientist, Antibody Discovery & Engineering
Scholar Rock
Cambridge, Massachusetts, United States
Principal Scientist, Protein Engineering
Merrimack
Cambridge, Massachusetts
Senior Scientist, Antibody Discovery
Compugen
San Francisco Bay Area
Development of antibody-based therapeutics against novel immuno-oncology targets. Expertise: Phage display, Lead optimization, Affinity maturation, Molecular biology, Structural biology, Structure-function relationships.
Scientist II, Antibody Discovery
Compugen
San Francisco Bay Area
Scientist I, Antibody Discovery
Compugen
San Francisco Bay Area
Postdoctoral Research Associate
Los Alamos National Laboratory
Los Alamos
Development of species-specific antibodies against bacteria in human gut by phage display and next generation sequencing. Potential applications in metagenomics and diagnostics/therapeutics. Development of specific, sensitive, and stable antibodies for direct detection of tuberculosis pathogen biomarkers using phage and yeast display and flow cytometry.
Postdoctoral Researcher
The Ohio State University
Columbus, Ohio Area
Computational modeling of protein-ligand interactions using molecular docking and molecular dynamics simulations. Structure-based design of enzyme active sites to tailor substrate specificity. Investigation of catalytic mechanism by hybrid quantum mechanical / molecular mechanics studies.
Education
The Ohio State University
Biological Chemistry
Dissertation: Biochemical, mechanistic, and structural characterization of DNA polymerase X from African Swine Fever Virus. Advisor: Prof. Ming-Daw Tsai Awards: Preston G. Hoff Fellowship for excellence in research.
Indian Institute of Technology, Kanpur
Chemistry
Dissertation: Identification and characterization of ATCUN-like motifs by crystal structure and sequence analysis. Advisor: Prof. R. Sankararamakrishnan
Sandeep Kumar's Contact Information
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