Jun Cui
Director, Search & Evaluation APAC External Scientific Innovation @ Johnson & Johnson Innovative Medicine
China
Pudong
Biotechnology
Molecular Biology, Cell Culture, Genetics, Stem Cells, Mouse Models, Lifesciences, Cancer, Life Sciences, recombinant DNA technology, qPCR, Microarray Analysis, Molecular Cloning, Developmental Biology, Genome editing, Reproductive Biology, Protein Purification, FACS analysis, Next generation sequencing analysis, iPS, DNA Sequencing
Experience

VP, Head of Translational Science
Shanghai, China
Overseeing the company’s translational research on novel cell therapies of tumor infiltrating lymphocytes/TILs, allogeneic and in-vivo CAR-T in the therapeutic areas of solid/liquid tumors and autoimmune diseases; Designing translational strategies and endpoints in first-in-human IIT, IND and pivotal clinical trials; Leading clinical biomarker discovery, correlative studies, BA and PKPD analysis; Built the company's product analytical capacity to support process and CMC development to enter IIT/IND clinical trials;

Research Scientist II/III, group leader
Emeryville, CA
Led a team of scientists to develop TCR mimics and CAR T cell pipelines using company's ARTEMIS T cell therapy platform to target B-cell malignancies and solid tumors, supported IND-enabling pre-clinical studies and first-in-human clinical studies, managed collaborations with internal/external teams in new technology development.

Research Scientist in Dept. of Cell Biology & Neuroscience
Bozeman, MT
- Developed ES/iPS cell-based assays for neurotoxicity tests and high throughput drug screens. - Engineered human ES/iPS cells using TALENs and CRISPRs. Built customized NGS pipelines for mutation discovery in human cell lines, tissue genotyping, genome recombination detection. - Differentiated DA neurons from stem cells in pre-clinical studies. - Studied human germ cell regeneration in xenotransplantation systems.

Postdoctoral Scholar
Stanford, CA
- Focused on deploying the new genome editing techniques (TALEN and CRISPR) in mammalian cells to create customized knock-in/knock-out cell lines. - Developed reporter pluripotent stem cell lines for lineage tracking and cell-based assays. - Built cell-based model systems by differentiating human pluripotent stem cells into specific cell types to study human diseases affecting the development or function of dopaminergic neurons and early gametes. Advisor: Renee Reijo Pera
Jun Cui's Contact Information
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