Jun Ren
Senior Scientist @ AstraZeneca
About
A driven scientist with a multi-disciplinary background in Immuno-Oncology, Cell therapy, Tumor Microenvironment, and Vascular Biology. Strong scientific, technical, and project management qualifications in the biopharmaceutical industry and academia. Skilled in the design and implementation of research strategy and managing multi-disciplinary research programs for the investigation of cancer therapy. 12+ years experience of in vitro, pre-clinical, and clinical translational research space. Solid track record in project management and demonstrated academic achievement evidenced by publications in high-impact journals. Passionate about exploring novel therapeutic interventions and applying principles established in basic science to making real-life medicine. https://www.cancerresearch.org/scientists/cri-funding-directory/jun-ren-phd
United States
Washington DC-Baltimore Area
Biotechnology
Immuno-oncology, Primary Cells, Technical Leadership, Technology Evaluation, Team Collaboration, Organization Skills, Genome Editing, Genetic Engineering, Ex Vivo, Cell Therapy, Cancer Immunotherapy, Oral Communication, Leadership, In Vitro, Hematology, Communication, Business Development, RNAseq, Scientific Analysis, Research and Development (R&D)
Experience
Senior Scientist
AstraZeneca
Clinical ICC Discovery, Oncology R&D
Editorial Board
Translational Oncology (TRANON)
Review Editor
Frontiers in Immunology - Cancer Immunity and Immunotherapy
Review Editor
Frontiers in Oncology - Cancer Molecular Targets and Therapeutics
Scientific Director
Dynamic Cell Therapies, Inc.
Boston, Massachusetts, United States
Develop next-generation CAR T Cell therapy for patients with liquid and solid tumors, allowing for multiplexing, titration, and modularity to deliver superior safety and efficacy to cancer patients.
Cancer Research Institute (CRI) - Dr. Keith Landesman Memorial Research Fellow
Harvard Medical School and Massachusetts General Hospital
Boston, Massachusetts, United States
• Improving the delivery and efficacy of CAR T cells in pediatric and adult brain tumors. • Reprogramming the tumor microenvironment to improve immunotherapy of glioblastoma.
Research Fellow
Harvard Medical School and Massachusetts General Hospital
• Develop effective therapies for pediatric ependymoma
American Heart Association (AHA) Research Fellow
University of Wisconsin-Madison
University of Wisconsin-Madison
Research Interests: • Pathogenesis of restenosis and aneurysm • Inflammatory chemokines involved intimal hyperplasia and aneurysm • Cross talk among smooth muscle cells, endothelial cells, adventitial cells, and circulating progenitor cells • Endothelial progenitor cells and circulating angiogenic cells • Gene (viral and non-viral) and Cell therapy Research Projects: My projects focus on elucidating the mechanism underlying vascular smooth muscle cells-mediated injury response. Specifically, my study is to understand how stressed vascular smooth muscle cells cross talk with vascular wall cells and circulating cells in order to orchestrate vascular injury response using angioplasty models, and develope gene and cell therapies to speed up recovery of blood vessels.
Research Assistant
University of Wisconsin-Madison
University of Wisconsin-Madison
My major research has been focused on the pathogenesis of vascular diseases including intimal hyperplasia and aneurysm. Specifically, I focus on chemokines expression, cross-talk among smooth muscle cells, endothelial cells, adventitial cells, and circulating progenitor cells during neointima formation in vitro and in vivo. In addition, I also put my effort to develop gene therapies against intimal hyperplasia using polyelectrolyte multilayers/DNA-coated catheter balloons, and cell therapy for a speedy recovery of injured blood vessels.
Business Development Specialist
Medtronic
Guangzhou, Guangdong, China
Medtronic Cardiovascular Group
Research Assistant
Sun Yat-sen University
Guangzhou, Guangdong, China
Research projects: • Regulation of the Legionella pneumophila Dps homolog by iron and involved during multiple stress tolerance. • The role of effector protein (LegK3) of Legionella pneumophila between pathogen-host interaction. • Characterization of the LysR-type transcriptional regulator LpvcR of Legionella pneumophila.
Education
Harvard Medical School
Immuno-Oncology, Tumor Microenvironment, CAR T-cel therapy
Postdoctoral Research Fellow in Immuno-oncology, Cell therapy, and Tumor Microenvironment, and Vascular Biology.
University of Wisconsin-Madison
Vascular Biology
Ph.D in Vascular Biology, Gene and Cell therapy.
Sun Yat-sen University
Medical Microbiology and Bacteriology
MS in Microbiotechnology
Jun Ren's Contact Information
Phone
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