Josie Yao
Project Manager-Preclinical and CMC @ Henlius
China
Xuhui District
Biotechnology
Antibody discovery, FACS analysis, Phage library display, Antibody engeering, Assay development for antibody potency evaluation, Make and design plan of biosimilar and innovative in preclinical stage of
Experience
Project Manager-Preclinical and CMC
Henlius
PM Dept
Project Manager of Therapeutic Ab (Biosimilar/Innovative) 1. Established the CMC timeline and coordinate with PD and Analytical Dept to meet the company’s goal. 2. Organized the tech-transferring from engineering run to GMP run. 3. Designed the plan of non-clinical study: PK and safety evaluation, communicated with CRO, review the total of report (including PK, ADA, repeated-dose toxicity study, etc). 4. Assisted RA on IND filing, including documents preparation, site inspection.
Senior Scientist in R&D Dept.
Henlius
Theraputic antibody early-stage discovery, include phage library, cDNA of viable region cloning, functional assay development (immunotherapyand tumor associated target ), stable line,etc.
Scientist in Dept PEP (Protein Expression and Purification)
Dragonfly (shanghai) Biomedicine Co,Ltd
Shanghai
Protein expression in mammalian and insect cells, purification, hybridoma related tech.
Research Associate
Shanghai Institute of Medica Meteria, Chinese Academy of Sciences
Shanghai
Discovery of chemical inhibitor of anti-tumor target , including: high throughput sreening, functional assay in vitro. Target validation.
Josie Yao's Contact Information
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