Jose Perez, Ph.D.

Director, Cell Pharmacology @ C4 Therapeutics, Inc.

About

Cellular/in vitro Pharmacology Director with extensive experience leading teams in the development of therapeutic leads. Experience working in large Pharma, Biotech, and Not-for-Profit Research Institutions. Successfully led teams in both Molecular/Cellular and Biochemical assay development and execution. Developed and managed relationships with external Partners and CROs to maximize effectiveness and efficiencies towards our shared objectives. Managed projects within the portfolio ensuring timely delivery of quality results, assemble and presented results to Senior Leadership to enable informed data driven discussions and decision making.

Country

United States

City

North Easton

Industry

Biotechnology

Skill

Experimental Design, Organization Skills, Data Interpretation, Cancer Therapeutics, Program Leadership, Regulatory Filings, Easily Adaptable, Team Leadership, Multiple Sites, Strategic Thinking, Multi-disciplinary Teams, Research Skills, Cross-functional Collaborations, Cellular Assays, Free Thinking, Analyze Information, B cells, Research Management, Project Teams, Trusting Relationships

Experience

Director, Cell Pharmacology

C4 Therapeutics, Inc.

2022-1 - Present · 4 yrs 9 mos

Watertown, Massachusetts, United States

Associate Director, Cell Pharmacology

C4 Therapeutics, Inc.

2018-5 - 2021-12 · 3 yrs 8 mos

Watertown, MA

• Joined C4T to learn the Targeted Protein Degradation (TPD) platform as a new modality in therapeutics development • Led a matrixed team supporting external collaboration partner projects, and internal platform development efforts • Co-builder and subsequent Coordinator for CRO Biology efforts supporting C4T target portfolio: 3 International, & 1 USA based CROs

Director, Cellular Pharmacology

Broad Institute of MIT and Harvard

2014-4 - 2018-5 · 4 yrs 2 mos

Cambridge, MA

Led a team of 12 Research Scientists: Ph.D., M.S., & B.S. • Provide functional line execution in Cellular Biology and Pharmacology across CDoT for programs in Inflammation/Immunology, Autophagy, Type 2 Diabetes, Degenerative Kidney Disease • Target validation, assay development and early therapeutics optimization Center for the Development of Therapeutics

Manager of Assay and Early Candidate Development

Broad Institute of MIT and Harvard

2009-4 - 2014-4 · 5 yrs 1 mo

Cambridge, MA

• Focused on the development of disease relevant in vitro assays and the discovery of new pre-clinical therapeutic agents • Comprehensive screening center for the NIH Molecular Libraries Program executing 119 programs, 1100 secondary assays, and delivering 49 chemical probes in 6 years • Assumed P.I. role on NIH R01 grant focused on the identification of selective CD40 signaling inhibitors

Grant Reviewer

MSCRF/Tedco

2009 - 2018 · 9 yrs

Senior Principal Scientist

Pfizer

2003-4 - 2009-3 · 6 yrs

Lead Generation Group: Biochemical and Cell based Assay Development & cross Therapeutic area SAR support.

Senior Principal Scientist

Pfizer Global Research and Development

1999-1 - 2003-4 · 4 yrs 4 mos

Inflammation Biology: Exploratory Biology focused on Cytokine and GPCR Signal Transduction; Kinase Signal transduction; Molecular & Cellular Biology and Biochemical & Cellular Assay Development; Reagent Generation & Protein Purification;

Principal Scientist

Pfizer Global R&D

1996-6 - 1998-12 · 2 yrs 7 mos

Drug Pfinder: HTS Assay Development and execution; Collaboration with external Academic and Biotech researchers exploring unprecedented pharmaceutical targets.