Jingzhi Lu
Staff Scientist, Head of Chemistry @ Element Biosciences
About
Material/organic chemist with good publication track record and expertise/skills in: • Multi-step modern organic synthesis • Chromophore chemistry • Photocatalysis, photophysics and photochemistry • Product development • Failure and root cause analysis • Porous materials • Nanofabrication and 2D material field effect transistors (FETs) • Colloidal nanomaterials
United States
San Diego
Biotechnology
Organic Synthesis, Surface Chemistry, Materials Science, Sequencing, IEX, SEC, Fluorescence Microscopy, Fluorescence Spectroscopy, UV/Vis Spectroscopy, LC-MS, Reverse phase HPLC, Chemistry, Data Analysis, HPLC, NMR, Nanotechnology, Nuclear Magnetic Resonance (NMR), Research, Microsoft Office, Microsoft Word
Experience

Staff Scientist, Head of Chemistry
San Diego, California, United States
Oversee a team of PhD scientists, driving the development of cutting-edge dyes, bioconjugates, and integrated chemical solutions to support Element platforms. • Strategic Leadership: Drive long-term chemistry roadmap and innovation strategy aligned with product and platform goals. • Molecular Design: Invent and synthesize multifunctional small and large molecules, including custom dyes, linkers, and probes tailored for Element’s platforms. • Bio-Conjugation & Assembly: Develop robust solutions for biomolecular conjugation, surface chemistry, and bio-assembly, enabling high-sensitivity detection and targeted biological interactions. • Bioanalysis: Build integrated analytical chemistry solutions that enhance molecular detection, quantification, and characterization for reagent development. • Platform Integration: Collaborate cross-functionally with biology, engineering, and informatics teams to create next generation biological tools.

Staff Scientist/Manager
San Diego, California, United States
• Lead the molecular design, synthesis and scale-up of fine-tuned functional dyes to enable new hardware design and improve NGS sequencing metrics. • Lead the development of sophisticated macromolecular assemblies to improve signal-to-noise ratio in NGS sequencing. • Lead the development of cocktail formulation to mitigate irradiation-induced system ageing. • Lead the development of surface coating chemistry and scale-up process. • Be as chemistry expert to support cross-functional teams for reagent/material selection and testing.

Senior Scientist
San Diego, California, United States
• Lead the design/development of novel, and expansion of existing chemistries (including small molecule, macromolecule and nucleotide), in line with the requirements of current and future product needs. • Lead design/development of surface chemistry (including both small molecule/macromolecule functionalization and nanoparticle deposition) for hardware consumable to enable new NGS application. • In-depth research of dye photophysics and photochemistry. • Research and development of purification strategies/techniques for small molecule, macromolecule and biomolecules with varying physical properties. • Design and conduct experiments to determine underlying reaction mechanisms, cause and effect, failure modes. • Contribute to decisions of product development process through effective communication of experimental design, results, and conclusions. • Contribute to the development of intellectual property

R&D Material Science Project Lead
San Diego, California, United States
• Lead development of polymer composites and coating materials • Lead development of polymer-based solid-state electrolyte • Lead fundamental study of material structure-(mechanical/electrical/chemical) property relationship • Develop tooling and quantitative analytical method for manufacturing quality control • Optimize manufacturing process using design of experiments (DOE) • Lead failure analysis, root cause study and solution development/validation

Postdoctoral Researcher
San Diego, California, United States
• Target guided optimization of formulation of bulk polymer composites and coating materials • Development of tooling and test method for manufacturing quality control • Design of experiments (DOEs) for optimization of manufacturing process • Failure analysis, root cause study and solution development for products

Ph.D. in chemistry
University of Nebraska-Lincoln
• Develop organic chromophores for photoredox and energy transfer catalysis • Explore supramolecular interaction and photophysics in organic photocatalysis • Develop porous polymeric materials for gas storage/separation, energy storage and catalysis • Use nanofabrication and surface chemistry to enable field effect transistors with light-responsive properties.
Jingzhi Lu's Contact Information
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