Jiansheng Wu
SVP, Head of CRO Services @ WuXi Biologics
About
Seasoned executive with over 20 years of experience in the biotech and biopharmaceutical industry。 Proven leadership in managing multidisciplinary teams and accelerating drug discovery pipelines through innovative technologies and platforms. Deep expertise in biologics, including mAb, BsAb, Fc fusions, TCR, ScFv, VHH, Fab and other recombinant proteins.
United States
San Francisco Bay Area
Biotechnology
Protein Purification, Protein Chemistry, Antibodies, Protein Expression, Drug Development, Biotechnology
Experience

SVP, Head of CRO Services
Shanghai, China, San Francisco, USA
SVP, Head of CRO Services October 2024 - Present VP, Head of Protein Sciences July 2021 - October 2024 • Lead multidisciplinary teams including antibody discovery, protein production and engineering, cell based assay, and in vivo pharmacology teams, totaling 500+ scientists. • Define and implement strategies for rapid and sustained revenue growth, doubling revenue in less than 3 years. • Build global project management, business development and marketing teams for CRO services. • Accelerate clients’ biologics drug development, ensuring a smooth transition from discovery to CMC. • Develop cutting-edge technologies for antibody discovery and protein production services • Innovate continuously to advance protein and antibody production services, establishing and maintaining industry leadership

Principal Scientific Manager II
Genentech
South San Francisco, California, United States
Genentech, South San Francisco April 2006 - June 2021 Principle Scientific Manager II April 2021 - June 2021 Principle Scientific Manager July 2016 - March 2021 Senior Scientist January 2014 - June 2016 Scientist April 2006 - January 2014 • Participated in 50+ drug development projects across oncology, immunology, infectious disease and neurodegeneration. • Led multiple teams in the purification of proteins and antibodies. • Developed high-throughput purification platforms for monoclonal antibody and Fab fragments. • Established high-throughput protein purification platforms for His, GST, Flag and Fc-tagged proteins expressed in E.coli, insect, and mammalian systems. • Led protein outsourcing efforts supporting both large molecule (LM) and small molecule (SM) projects. • Built external protein production capacity at multiple CROs, including mammalian transient/stable expression and purification, and E.coli/BEVS expression and purification. • Oversaw 10+ internal FTE and 60+ external FTE for protein production

Staff Scientist
GeneSoft
South San Francisco
Staff Scientist

Postdoc
UCLA
Los Angeles
Postdoc
Jiansheng Wu's Contact Information
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