JI CHANG

Research Fellow in Biomedical department @ Nitta Gelatin Inc

About

Currently, I work as a scientist and business development professional in the biomedical field, focusing on biomedical products and equipment. My responsibilities include providing (1) technical support, (2) managing international sales activities, and (3) developing novel and next-generation biomaterials, particularly collagen- and gelatin-based raw materials, through collaborations with existing and prospective business partners worldwide.This role has been challenging, as it requires a different mindset and approach from those cultivated during my academic career. However, I believe these experiences have significantly strengthened both my communication skills and my ability to address complex challenges. Combined with my multilingual proficiency in Mandarin Chinese, English, French, and Japanese, they have provided me with strong confidence and a broader perspective that will support my future return to the pharmaceutical and biotechnology sectors in an international environment.Beyond my career aspirations, I have a strong desire to broaden my horizons through cultural and social experiences in different countries. Learning French (next one would be other European languages, I love it!) and attaining the DELF B1 level marked the beginning of this journey, and it has further strengthened my interest in international collaboration. I greatly value opportunities to communicate and work with people from diverse backgrounds, as these experiences enrich our both personal growths and professional developments. Thank you for giving me the opportunity to share and exchange experiences with you all!

Country

Japan

City

Osaka

Industry

Biotechnology

Skill

Presentation Skills, Data Analysis, Programming, Scientific Writing, Marketing Research, Medical Research, Japanese as a second language, French as a second language, English as a Second Language (ESL)

Experience

Research Fellow in Biomedical department

Nitta Gelatin Inc

2025-11 - Present · 11 mos

大阪府, 日本

Education

Tohoku University

Medical Science

2020-4 - 2024-3 · 4 yrs

1. Dissertation Dissertation titled: “SETDB1 represses H3K4/H3K9me3 bivalent genes through ubiquitination-dependent and -independent mechanisms.” 2. Publication List > Review Articles 1) Combined issue of Volume 132, No. 2 and Volume 133, No. 1, The Journal of Tohoku Medical Society, Tohoku Med J 133: 76, 2021. > Peer-Reviewed Publications 1) Glucose-activated JMJD1A drives visceral adipogenesis via α-ketoglutarate-dependent chromatin remodeling. Cell Reports 44(8): 116060. 2) Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveals a context-dependent role for its methyltransferase activity during adipogenesis. Genes & Cells 26(7): 513–529. 3) Spatiotemporal dynamics of the SETD5-containing NCoR–HDAC3 complex determine enhancer activation during adipogenesis. Nature Communications 12(1): 7045. 4) MYPT1–PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment during beige adipogenesis. Nature Communications 13(1): 5715.

The University of Tokyo

Medical Science

2015-4 - 2017-3 · 2 yrs

1. Dissertation Dissertation titled: “Elucidation of the molecular mechanism underlying Dab2-induced enhancement of osteoclastogenesis.” 2. Research Experience and Technical Expertise Elucidation of the molecular mechanism underlying Dab2-induced enhancement of osteoclastogenesis > Demonstrated that overexpression of Disabled-2 isoforms (DAB2A/DAB2B) in primary bone marrow–derived cells enhances osteoclast differentiation, and identified that this effect is mediated specifically by DAB2B through inhibition of the ERK pathway, whereas DAB2A does not exert this effect. > Established DAB2 isoform–specific knockout RAW 264.7 cells (murine macrophage leukemia cell line) using the CRISPR/Cas9 genome-editing system.

Beijing Forestry University

Biology and Biotechnology

2010-9 - 2014-7 · 3 yrs 11 mos

Research Experience and Technical Expertise 1) Granulosa Cell Proliferation in Wild Ground Squirrels > Investigated seasonal changes in cyclin (D1–D3), PCNA, and Ki67 expression using IHC and western blotting. 2) microRNA Regulation of Vascular Cambium in Cunninghamia lanceolata > Prepared semithin/paraffin sections for morphological analysis and evaluated germination rates under light/dark conditions. 3) Stability & Antimicrobial Properties of Platycladus orientalis Volatile Oils > Extracted volatile oils, assessed stability via spectrophotometry, and evaluated antimicrobial activity against multiple bacterial strains.