J Ross, Ph.D.
Co-Founder and CEO @ Alleo Labs
About
I am passionate about building software to discover safe and effective therapies for patients with neurodegeneration. Here’s a link to my PBS interview, discussing dementia: https://to.pbs.org/3j3ZlA4 At Alleo Labs, my research focuses on understanding the principles behind complex brain diseases and guiding therapeutic programs through preclinical and clinical stages, while embracing the challenges of being a drug hunter. At the NIH, I developed data mining and machine learning software to analyze DNA that regulates brain development. It was an exciting opportunity to decode a "regulatory language" in our DNA and gain insights into basic neuroscience and stem cell biology.
United States
San Francisco
Non-profit Organization Management
Cell Biology, Neuroscience, Molecular Biology, Immunohistochemistry, Machine Learning, Fluorescence Microscopy, Scientific Writing, Bioinformatics, R, Python, Molecular Cloning, Java, Matlab, Graphic Design, Web Design, Web Applications, HTML, Statistical Data Analysis, Molecular Genetics, Digital Photography
Experience
Co-Founder and CEO
Alleo Labs
San Francisco, California, United States
Board Member
Alzheimer's Association®
New York City Metropolitan Area
Mentor
Nucleate
VP, Head of Neuroscience
Immuneering Corporation
San Francisco, California, United States
• Co-led Immuneering to a $129.4M IPO exit in 2021 (NASDAQ: IMRX) and worked closely with executive team on corporate strategy. • Led a cross-functional team of neuroscientists, bench scientists, med-chemists, and computational biologists to advance preclinical drug discovery for neurodegeneration. • Managed the development of AI platform to develop allosteric, brain-penetrant inhibitors targeting a novel deubiquitinase. • Established an advisor team of ex-Merck, AstraZeneca, and Acadia drug hunters. • Formed research collaboration with Amsterdam University Medical Centers (UMC) to study neurodegeneration.
Head of Neuroscience
Immuneering Corporation
New York, New York, United States
• Managed key decisions in characterizing novel drug targets and initiating internal CNS drug discovery programs. • Led optimization of AI drug discovery platform for target ID and hit ID (small-molecule). • Established and led a drug discovery partnership with Astex Pharmaceuticals, a wholly owned subsidiary of Otsuka Pharmaceutical of Japan. • Contributed to the company's portfolio during two priced rounds: $20M Series A and $62M Series B.
Director of Translational Medicine
Immuneering Corporation
New York, New York
• Led partnership with the Dementia Discovery Fund to study Alzheimer's disease. • Managed a team of computational biologists developing drug discovery platforms. • Developed algorithms for Alzheimer's patient stratification and biomarker discovery. • Founded the company's neuroscience drug discovery division (now Alleo Labs).
Associate Director of Translational Medicine
Immuneering Corporation
Greater New York City Area
At Immuneering, we are trusted advisors to the world’s leading pharmaceutical companies, pioneering new ways to use biological and clinical data to enhance patient outcome. My team and I have worked with pharmaceutical clients across a number of human neurological disorders, including Huntington disease, Rett Syndrome, Dystonia, and Parkinson's disease.
Neuroscientist and Computational Biologist, NINDS
The National Institutes of Health
Bethesda, Maryland
• Built and implemented a bioinformatic pipeline for analysis of over 2000 DNA enhancers • Developed an AI model to predict phenotypic behavior of DNA enhancers and generate synthetic DNA enhancers to control the spatiotemporal expression of CNS transcription factor genes. • Published on one of first use cases of synthetic biology for DNA enhancers that govern gene expression in the CNS and PNS
PhD student
Brown University
Research Associate
University of Michigan
Ann Arbor, Michigan
Computer Consultant
University of Michigan
Ann Arbor, Michigan
Intern
Ford Motor Company
Dearborn, Michigan
I completed summer internships in the Finance and Quality Control departments.
Education
Brown University
Neuroscience
University of Michigan
Cellular, Molecular and Developmental Biology
J Ross, Ph.D.'s Contact Information
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