Jason Charish

As Endogena Therapeutic’s Director of Translational Medicine, I have experience managing the analysis, interpretation and presentation of clinical data from first-in-human trials, assisting in the design of future clinical trials and preparing scientific and regulatory documents key for moving projects forward. I am passionate about harnessing insights from translational research and applying them to the analysis and interpretation of disease biomarkers in clinical studies. Previously, as Head of in-vivo Pharmacology, I led the design, execution, and analysis of in-house pre-clinical studies together with managing outsourced activities with academic and CRO partners. My work helped advance candidate molecules towards the clinic and contributed to two successful IND applications and one fast-track designation approval. Prior to focusing on in-vitro and in-vivo proof-of-concept studies in drug discovery and development research, I received my MSc and PhD from the University of Toronto and did post-doctoral work at the University Health Network. I specialized in models of human diseases with a focus on the retina. My research has contributed to peer-reviewed publications in the fields of retinal disease, molecular biology, stroke, cancer, multiple sclerosis, COVID and brain/eye development