Jacques S.

Jacques S.

Principal Scientist and Platform Team Lead @ General Proximity

About

Passionate chemical biologist with twelve years of experience (eight academia and four industry) in ligand discovery and assay development, with a 6-year focus on heterobifunctional molecules. I thrive at the interface between chemistry and biology and enjoy working with both teams to optimize discovery pipelines. I love making molecules as much as testing them. I strongly support equal opportunity and sharing my love for science to give opportunities to all to start a career in STEM.

Country

United States

City

San Francisco

Industry

Biotechnology

Skill

Drug Discovery, Assay Development, Synthetic Chemistry, Chemical Biology, Biophysics, Project Management, Organic Synthesis, NMR, Organic Chemistry, Chemistry, Analytical Chemistry, UV/Vis, IR, HPLC, Chromatography, Catalysis, Spectroscopy, Medicinal Chemistry, LC-MS, Biochemistry

Experience

General Proximity

Principal Scientist and Platform Team Lead

General Proximity

LinkedIn
2025-12 - Present · 9 mos

San Francisco Bay Area

General Proximity

Associate Principal Scientist and Platform Lead

General Proximity

LinkedIn
2024-7 - 2026-1 · 1 yr 7 mos

San Francisco Bay Area

Next gen IPM incoming 🤫. Empowering an incredible team of people to take Induced Proximity Medicine to the next level! Our team focuses on Structural Biology and Biophysics, Screening and MoA elucidation.

Siduma Therapeutics

Principal Scientist

Siduma Therapeutics

2023-5 - 2024-5 · 1 yr 1 mo

Development of a new induced proximity platform. Ligand discovery and optimization, SAR and probe design. Development of target engagement assays (SPR, ITC, FP assays) and proximity-based assays (HTRF/TR-FRET, alphaLISA).

Yale University

Associate Research Scientist (Craig Crews Lab)

Yale University

LinkedIn
2023-2 - 2023-5 · 4 mos

New Haven, Connecticut, United States

Yale University

Postdoctoral Fellow (Craig Crews lab)

Yale University

LinkedIn
2020-1 - 2023-2 · 3 yrs 2 mos

New Haven, United States

University of Geneva

PhD Student in Chemistry (Winssinger lab)

University of Geneva

LinkedIn
2014-9 - 2019-10 · 5 yrs 2 mos
Cell Cycle Biosensors and Inhibitors Group IBMM

MScRes Intern

Cell Cycle Biosensors and Inhibitors Group IBMM

2014-3 - 2014-8 · 6 mos

Montpellier Area, France

Synthesis and Characterization of Photoactivable CDK4/Cyclin Peptide based Fluorescent Probe

GSK

Intern in the Chemical Biology Group

GSK

LinkedIn
2012-7 - 2013-7 · 1 yr 1 mo

Raleigh-Durham, North Carolina Area

Synthesis of Free and Linkable Kinase Inhibitors for Proteomic Profiling

Education

Yale University

Yale University

LinkedIn

Chemical Biology

2020-1 - 2023-5 · 3 yrs 5 mos
University of Geneva

University of Geneva

LinkedIn

Chemical Biology

2014 - 2019 · 5 yrs
Ecole Nationale Supérieure de Chimie de Montpellier

Ecole Nationale Supérieure de Chimie de Montpellier

LinkedIn

Chemitry, Biology, Medicinal Chemistry

2013 - 2014 · 1 yr

Medicinal Chemistry: Vectorisation, Drug targets, Toxicology, Pharmacokinetics Biology: Genetics and Cell Signaling Chemistry: Peptide Synthesis, Stereoselective Synthesis

Ecole Nationale Supérieure de Chimie de Montpellier

Ecole Nationale Supérieure de Chimie de Montpellier

LinkedIn

Chemistry

2010 - 2012 · 2 yrs

Jacques S.'s Contact Information

Email

******@***.com

Phone

(**) *** ****

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