Hu (Ivy) Ye

Built site, team and pipeline from scratch -Subsidiary site planning, preparation and build. The site includes a clean room which gained environment impact assessment approval and passed 3rd party assessment -Established the team: R&D, Production, Quality, Supply chain and HR -Led an innovative cardiovascular interventional system and consumable development project: developed specifications and engineering prototype in 6 months, launched a successful animal experiment in 1 year -Built up a quality system in 6 months -Upstream marketing, product/pipeline planning and competitive intelligence -Budget planning

Venture Investment: Deal sourcing, assessment, execution and portfolio management − Invested 7 innovative medtech or medical services companies. (2 exited with >30% annual return) − Areas of investment included cardiovascular, interventional oncology, ear nose & throat (ENT), innovative ablation, day surgery and renal analysis chain etc. BD & Strategy − Overall external partnership strategy − Sector analysis, market research and innovative technology sourcing: By therapeutic area: Orthopedics (sports medicine, spine); Gastrointestinal diseases; Gynecology (innovative ablation for benign uterine disease); Cardiology (LAA occlusion, wearable Holter, mitral valve repair); Hepatology (TACE, ultrasonic elastography); Aortic and peripheral vascular (thrombectomy, stent); Diabetes (CGM, insulin pump etc.); Lung cancer (diagnosis to treatment) By innovative technology: 3D printing, liquid biopsy, AI, surgical robotics, innovative ablation − BD Business partner for cardiovascular group People management − Recruitment, training and management for interns and analysts

Business Development & Strategy

• Partnership and M&A − Developed external partnership strategy for an MNC Pharmaco: scanned along value chain and prepared short list of potential M&A targets − Developed Asia Pacific strategy for a leading biologic company: assessed BD options to maximize portfolio value, determined optimal go-to-market and reviewed partnership model for different markets • Commercial strategy and implementation − Developed commercial strategy and implementation plan for a MNC medical device company: prioritized pipeline to fit unmet medical needs, built an integrated go-to-market model and implementation plan to realize 150 Mn USD synergy by 2020 − Organized strategy workshop for a leading domestic lighting company • R&D capability development − Re-organized China regulatory affairs department into an efficient and effective RA organization for an MNC Pharmaco − Organized R&D workshop for a leading generic drug company • Project management − Conducted project management for a 2-year transformation program of a joint stock bank

• Established a procedure for integrating multiple image modalities (PET, CT, MRI) • Validated a PET brain tracer and evaluated drug dose on animal model • Presented the research project in department meeting and campus-wide poster session • Selected to give poster presentation at Society of Nuclear Medicine annual meeting

• Led discussion sessions and lab sessions

• Winner of UCLA 2012 Venture Team Competition; Awarded 30k US dollars to commercialize the technology • Proposed and presented a business plan for a technology which non-invasively detects intracranial hypertension with ultrasound

• Coordinated the emerging company technology presentation in investor and partnership conferences

• Dissertation: Methods for Quantitative Clinic and Preclinical Brain Positron Emission Tomography (PET)/CT Imaging − Developed a method of movement correction for Clinical Positron Emission Topography(PET)/CT dynamic scan − Designed and conducted PET and MRI experiment, developed image processing procedures and math models to systematically evaluate the influence of different chemo therapy drugs on brain metabolism in rats. Collaborated with physicians, biologists and mathematicians • Published 3 journal articles; Selected to give oral presentations and poster presentations at Society of Nuclear Medicine annual meeting for 4 times

• Graduated with highest honor from Honor Engineering Mixed Class (Top 5% of engineering students), Chu Kochen Honor’s College; Excellent Graduate of Zhejiang Province • Mathematic modeling competitions: 1st Prize at province level (Zhejiang), 2nd Prize at national level (China)