houman dehghani

* Responsible for planning, organizing and directing biological projects for commercial applications and overseeing the performance of standard and custom-designed GLP/cGMP studies and assays. * Responsible for design and implementation of custom protocols for in vivo testing of pharmaceuticals. * Responsible for adherence to GLP/cGMP guidelines. * Responsible for preparation of final reports and recommendations for further testing and regulatory compliance for clients.

* Identified a hot-spot of homologous mitotic recombination on the genome of polyomavirus active in the process of transformation of cultured cells by polyomavirus. * Studied integration pattern of polyomavirus in cultured cells. * Characterized mouse B-cell proliferative, cytokine, and antibody responses following IL-10 stimulation in vitro. * Learned and utilized enzyme-linked immunosorbent assays (ELISA), H3-thymidine incorporation proliferation assays. * Worked on construction and cloning of a mutant thymidine kinase promoter. * Learned DNA cloning using plasmid vectors, SDS PAGE analysis, DNA/RNA isolation and detection.

Director, Cellular Resources Department overseeing three independent groups involved development of methodologies for detection and identification of adventitious contaminants and execution of viral clearance studies for process characterization as well as creation of master and working cell banks and generation of critical reagents.