Hengwei Chen

Dr. rer. nat. (PhD, Grade 0.7 – Magna cum laude) in Computational Life Science from the University of Bonn under the supervision of Prof. Dr. Jürgen Bajorath, affiliated with the Bonn-Aachen International Center for Information Technology & Lamarr Institute for Machine Learning and Artificial Intelligence. Currently working at BeOne Medicines (BeiGene) as an AIDD Research Investigator. With over five years of research experience and 12 peer-reviewed publications in AI-driven computational drug design and cheminformatics, my expertise centers on generative molecular design using advanced machine/deep learning technologies and chemical/biochemical language models. Applications include medicinal chemistry tasks such as predicting activity cliffs and highly potent compounds, target-specific molecule generation, and analogue series expansion toward higher potency. In addition to academic research, I bring one year of industrial experience developing an AI-driven platform for molecular bioactivity and ADMET prediction, collaborating with cross-functional R&D teams, and applying generative AI to 3D pocket-based molecular design. I am dedicated to leveraging my combined academic and industrial expertise in AI and life sciences to accelerate innovation in drug discovery.