Hao Liu
Senior Director in Drug Discovery and Cancer Biology @ Solve Therapeutics, Inc.
About
Ph. D-level Immunologist with 18 years of laboratory experience. Proven expertise in employing immunology, molecular biology skillsets, and in vivo animal model systems to drive the decision-making and project transition in the pre-clinical stages of drug development.
United States
San Diego
Biotechnology
Culture of Tumor Infiltrating Cells, Advanced Flow Cytometry Techniques, Stem Cell Research, Dendritic Cell Differentiation, Tumor Immunology, Cancer Immunotherapy, Molecular Biology Techiques, Stromal Cells, Antibodies, Flow Cytometry, Molecular Biology, Biochemistry, Confocal Microscopy, ELISA, Cancer Research, Cancer, Immunohistochemistry, Western Blotting, Vaccines, Science
Experience
Senior Director in Drug Discovery and Cancer Biology
Solve Therapeutics, Inc.
Director in Drug Discovery and Cancer Biology
Solve Therapeutics, Inc.
San Diego, CA
Senior Principal Scientist
Regor Therapeutics Group
San Diego County, CA
Lead a team to drive projects from target validation to the PCC stage. Manage the Competitive Intelligence team to monitor the competitive landscape and arrowhead the efforts of new target identification and proposal.
Principal Scientist
Regor Therapeutics Group
Sr. Scientist in Cancer Immunopharmacology
Pfizer
San Diego
Devoted to the decision making and project transition in the pre-clinical stages of drug development
Research Scientist / Postdoctoral Researcher
Moffitt Cancer Center
Tampa/St. Petersburg, Florida Area
Devoted to the combination targeted therapy and immunotherapy for the treatment of melanoma, and the pre-clinical investigation of novel immunotherapeutic agents for the treatment of melanoma and pancreatic adenocarcinoma. This includes tumor-based vaccine therapy, immune-activating antibodies: PD-1 and CD137, and autologous T cell therapy. Investigated the role of Notch, Wnt and AhR signaling pathway on the differentiation of dendritic cells (DCs) and myeloid-derived suppressor cells (MDSCs) in healthy animals and in the tumor environment.
PhD student
University of York
York, United Kingdom
Investigated the molecular and celluar mechanism of differentiation of CD11clo CD45RBhi regulatory dendentic cells (DCs) by using co-culture system of hematopoietic progenitors and stromal cells
Research Associate / Postgraduate student
University of Nottingham / University of Leicester
Nottingham, United Kingdom
Investigation on the characterization and function analysis of BCL11A, a transcriptional repressor; screen the potential interacting partner of BCL11A by using yeast-two-hybrid.
Research Associate
Shanghai Genomics
Shanghai, China
Construction of a small cDNA library containing genes of interest, screening potential candidate interactions by yeast-two-hybrid.
Education
University of York
Immunology
University of Leicester
Molecular Genetics
Shanghai University
Bioengineering and Biomedical Engineering
Hao Liu's Contact Information
Phone
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