Gaoyang Liang
Staff Scientist @ Salk Institute for Biological Studies
About
• Oncology scientist focused on developing novel therapeutic strategies through mechanistic and translational research.• Expertise in target identification and validation, mechanism-of-action studies, biomarker strategy development, and precision targeting approaches.• Deep understanding of tumor dependencies and therapeutic vulnerabilities, tumor–stroma signaling, functional genomics, and epigenetic and transcriptional regulation.• Experienced in leading multidisciplinary collaborations and advancing oncology research from discovery through preclinical development and translational strategy planning.
United States
San Diego
Biotechnology
Translational Research, Oncology, Cancer Therapeutics, Pre-clinical Studies, Drug Discovery, Cell Biology, Molecular Biology, Biochemistry, Western Blotting, Cell Culture, PCR, Protein Purification, Molecular Cloning, Protein Chemistry, Protein Expression, Cell, qPCR, Life Sciences, Confocal Microscopy, Immunohistochemistry
Experience
Staff Scientist
Salk Institute for Biological Studies
La Jolla, CA
• Lead a translational oncology program targeting epigenetic dependencies in pancreatic ductal adenocarcinoma (PDAC), driving strategy, execution, and cross-functional collaboration. • Direct mechanistic studies and develop therapeutic strategies, including rational combination approaches. • Evaluate precision delivery platforms (e.g. nanoparticle-based) for tumor-selective targeting, demonstrating improved therapeutic index with integrated pharmacodynamics and biomarker analyses.
Senior Research Associate
Salk Institute for Biological Studies
La Jolla, CA
• Led research evaluating epigenetic strategies to reprogram the PDAC microenvironment and overcome immunosuppression. • Defined cell-type-specific dependencies, elucidated mechanisms of action, and established rationale for combination with immunotherapies. • Coordinated collaborations, mentored junior scientists, published findings, and contributed to successful grant development.
Postdoctoral Research Associate
Salk Institute for Biological Studies
La Jolla, CA
• Investigated epigenetic drivers of stromal activation and pro-tumorigenic signaling in PDAC. • Identified key epigenetic/transcriptional programs, developed biomarker strategies, and demonstrated in vivo efficacy of epigenetic therapies. • Collaborated across research teams and mentored trainees.
Postdoctoral Fellow
Harvard Medical School
Boston, MA
Graduate Research Assistant
The University of North Carolina at Chapel Hill
Chapel Hill, NC
Education
The University of North Carolina at Chapel Hill
Biochemistry
Western University
Biochemistry
Sun Yat-sen University
Biochemistry
Gaoyang Liang's Contact Information
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