Frederic Van Gool
Head of Immunology @ Stealth Mode Biotech
About
As an Immunologist and Biotech Leader, I am driven by a passion for advancing cell therapy and immune tolerance research to create transformative therapies for patients. With a strong foundation in cellular immunology, drug development, and cell engineering, I have built and led high-performing teams to deliver scientific and strategic breakthroughs. My expertise lies in bridging cutting-edge research with therapeutic innovation, bringing together partnerships, internal R&D and external collaborations to develop next-generation immune therapies. I thrive in fast-paced biotech environments, guiding teams through discovery, preclinical development, and IND-enabling studies. What drives me is the opportunity to: • Empower teams to drive innovation from discovery to preclinical development • Advance our understanding of immune tolerance mechanisms and apply these insights to develop breakthrough therapies • Contribute to the advancement of novel therapies through scientific innovation and intellectual property development • Build strategic collaborations across academia and industry I look forward to connecting with professionals who share my passion for advancing science and translating research into impactful therapies.
United States
Philadelphia
Biotechnology
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Experience

Senior Director Discovery Science
South San Francisco, California, United States
• Company Builder & Leadership: Founding team member who built and managed the early discovery team, leading R&D from concept to validation. • Team Building & Leadership: Recruited, mentored, and led a high-performing scientific team driving innovation in early discovery, fostering a collaborative and goal-oriented environment. • Operational Leadership: Designed and built research labs and office spaces, overseeing EHS compliance, procurement, and facility management. • Strategic Portfolio Management: Partnered with C-level executives to evaluate scientific data and drive strategic portfolio decisions. • Scientific Innovation & IP Development: Spearheaded Treg cell therapy innovation, leading to multiple patent applications. • IND-Enabling Studies: Collaborated on IND-enabling studies for SBT-77-7101, advancing it toward clinical readiness. • External Innovation & Partnerships: Developed strategic collaborations with CROs, biotech, and academic partners, organizing scientific seminars with key opinion leaders and SAB members.

Adjunct Assistant Professor
UCSF Diabetes Center
Led independent and collaborative research projects focused on: • Foxp3 transcription factor regulation in immune tolerance • Development of preclinical mouse models for regulatory T cell function

Postdoctoral Research Scientist
San Francisco, California, United States
Laboratory of Jeffrey A. Bluestone, PhD • Identified the cross-talk between innate lymphoid cells and Treg cells • Elucidated mechanisms of Treg instability in pre-clinical mouse models of autoimmune diseases
Frederic Van Gool's Contact Information
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