Emma Crowley-Dolen, Ph.D.

Emma Crowley-Dolen, Ph.D.

Senior Scientist @ Akttyva Therapeutics

About

I am a chemical biologist working at the interface of enzymology, assay development, and drug discovery. My research and industry experience have focused on developing biochemical and cellular assays, characterizing enzyme function, and advancing small-molecule discovery programs through screening, chemical probe development, and inhibitor characterization. I am currently a Scientist at Akttyva Therapeutics, where I design and execute screening workflows to identify enzyme binders, inhibitors, and activators, while collaborating with multidisciplinary teams to translate experimental and computational insights into discovery strategies. Beyond the lab, I am an active science communicator and mentor. I volunteer with Skype a Scientist to share the drug discovery process with classrooms nationwide and enjoy helping students and early-career scientists explore paths in biomedical research. I am passionate about translating scientific discoveries into therapeutic solutions and connecting with professionals across biotech and pharma who are working to make a real-world impact. Outside of science, you can find me on the trails or running road races with the Cambridge Running Club. Let’s connect — I’d love to talk about drug discovery, biotech, or running!

Country

United States

City

Boston

Industry

Research

Skill

Scientific Experimentation, Research Supervision, Scientific Research, Scientific Communications, Compound prioritization, Project Management, Fluorescence Anisotropy, Differential scanning fluorimetry, Mentoring, Protein visualization, High Throughput Screening, Drug Discovery, Experimental Design, Cell Culture, Molecular Cloning, Scientific Writing, High-Performance Liquid Chromatography (HPLC), Gel Electrophoresis, Microsoft Word, Molecular Biology

Experience

Akttyva Therapeutics

Senior Scientist

Akttyva Therapeutics

LinkedIn
2026-7 - Present · 3 mos

Watertown, MA

Akttyva Therapeutics

Scientist

Akttyva Therapeutics

LinkedIn
2026-3 - 2026-7 · 5 mos

Watertown, MA

Harvard University

PHD Candidate

Harvard University

LinkedIn
2020-8 - 2026-3 · 5 yrs 8 mos

Cambridge, MA

My thesis work focused on developing small molecule inhibitors for an enzyme implicated in brain cancer and characterizing the biochemistry of this enzyme. I have experience in high-throughput screening, enzyme activity and binding assays, cell-based assays, and structure-guided design, in addition to a wide range of biochemical and molecular biology techniques.

Bucknell University

Undergraduate Researcher

Bucknell University

LinkedIn
2016-6 - 2020-8 · 4 yrs 3 mos

Lewisburg, PA

My undergraduate research focused on learning about how two amino acid point mutations in DNA methyltransferase I (DNMT1) impacted the structure and function of the enzyme. I used site-directed mutagenesis, protein expression, and protein purification to produce the mutated and wild-type DNMT1 proteins. To characterize the effects of these mutations, I employed electrophoretic mobility shift assays, plate-reader kinetics assays, and melting point assays. This research culminated in my undergraduate honors thesis and a publication in Biochemistry.

Education

Harvard University

Harvard University

LinkedIn

Chemical Biology

2020 - 2026 · 6 yrs
Bucknell University

Bucknell University

LinkedIn

Chemistry

2016 - 2020 · 4 yrs

Emma Crowley-Dolen, Ph.D.'s Contact Information

Email

******@***.com

Phone

(**) *** ****

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