Elaine Campbell

Sr Scientist @ CAGE Bio Inc.

About

I am a highly skilled Molecular Biologist/Biochemist with 18 years professional experience in pharmaceutical research and development. Throughout my career I have a demonstrated track record of creativity, strong leadership, analytical, and problem solving skills with the ability to communicate effectively to a wide variety of target audiences. I am experienced in assay development using mammalian cell culture, ex-vivo and in-vitro samples, biochemical assays, biomarker identification, clinical and pre-clinical testing, as well as formulation and process development. Each day I strive to innovate and deliver quality work to meet project goals and achieve positive results both within cross functional teams and independently within my organization. RESEARCH TECHNIQUES & SKILLS • Extensive experience with multiple tissue culture types (mammalian suspension, adherent and stratified cells, ex-vivo derived cell types, human whole blood) • Detailed knowledge of in-vitro model systems and assay design • Experience in multi-color Flow Cytometry (BD Canto), high throughput imaging (BD Pathway Imager, Amnis Imagestream) and FACS (BD Aria) • Experience in Inflammatory Biomarker Assay design and validation (Multiplex ELISA and RT-PCR arrays) • In-vivo experience including restraint, euthanasia and tissue/organ collection from rodents • Knowledge of Protein characterization techniques (Western blot, ELISA, bacterial expression systems) • Knowledge of Molecular Biology techniques including RNA and DNA isolation, RT-PCR, plasmid construction • Experience in microscopy (confocal, light, fluorescence and polarized light microscopy) • Detailed knowledge of Inflammation and Inflammatory pathways and their role in various disease states • Experience with collection and processing of clinical samples • Formulation and process development for small molecules, peptides and oligoneucleotides • Tech transfer and scale up for clinical manufacturing • Authoring and Reviewing documentation including SOPs, deviations, quality documents, manufacturing instructions and batch records • CRO/CMO coordination • Team leadership experience •Technical writing and effective communication skills

Country

United States

City

Dallas-Fort Worth Metroplex

Industry

Pharmaceuticals

Skill

Project Coordination, Biochemistry, Experimental Design, Research and Development (R&D), Investigation, Corrective and Preventive Action (CAPA), Analytical Skills, Attention to Detail, Method Development, Good Laboratory Practice (GLP), Global Cross-Functional Team Leadership, Cross-Functional Team Building, Cross-functional Coordination, Technical Reports, Cellular Communications, Biology, Pharmaceutical Formulation, Clinical Manufacturing, Communication, Presentation Skills

Experience

Sr Scientist

CAGE Bio Inc.

2024-3 - Present · 2 yrs 7 mos

Fort Worth, Texas, United States

Senior Formulation Scientist

Novartis

2017-9 - 2023-12 · 6 yrs 4 mos

Dallas/Fort Worth Area

Formulation planning and development for preclinical studies for a range of therapeutic targets.

Research Scientist III

Boehringer Ingelheim

2015-6 - 2017-9 · 2 yrs 4 mos

Ridgefield, CT

Research Scientist in Biotherapeutics/Immune Modulation & Cancer Immunology Development of functional in-vitro and ex-vivo assays for characterization of antibodies and validation of disease target models. Development of binding and competition assays for characterization of novel therapeutics Cell Culture techniques including: characterization, maintenance and isolation of primary cell lines In-vivo model support including tissue collection and processing and ex-vivo assay design

Research Scientist II

Boehringer Ingelheim

2012-11 - 2015-6 · 2 yrs 8 mos

Ridgefield, CT

Biomarker Research Scientist

Pfizer

2012-7 - 2012-11 · 5 mos

Pfizer Clinical Research Unit, New Haven, CT

Performed validation of in-vitro assays for biomarker analysis of clinical samples Handled intake, processing and analysis of samples from clinical trials Maintained and wrote SOPs, and other validation documents to support ongoing clinical trials

Research Scientist II

Alcon Laboratories

2007-2 - 2012-9 · 5 yrs 8 mos

Development of multiplex arrays for ocular surface biomarker discovery (protein and RNA based) Characterization of clinical samples to aid in establishing disease etiology for Dry Eye and Meibomian Gland Dysfunction using protein and RNA based multiplex assays Lead development of ocular surface models to identify, design and develop new therapies and establish mechanisms of action Provide technical expertise on target validation and bioassay development Provided innovative ideas, plans and products to assist in the development of a robust Dry Eye portfolio in line with unmet medical needs and business growth opportunities 4 Method of Invention (MOI) submissions on product ideation and methodologies

Research Assistant II

University of Texas Southwestern Medical Center

2004-8 - 2007-2 · 2 yrs 7 mos

Management of multiple cell lines for high throughput bioassays across multiple functional groups Provided technical expertise to conduct cellular and molecular based bioassays to characterize ligand interactions (including calcium transport, cAMP production, receptor activation and lipid synthesis assays)

Graduate Research Assistant

University of Texas at Tyler Health Center/ Stephen F Austin State University

2003-1 - 2004-8 · 1 yr 8 mos

Research focus: Biochemical and Molecular Biological analysis of signaling pathways utilized by inflammatory cytokines and their effect on Surfactant Protein B Completed Thesis "Investigation of the Signaling Pathways involved in TNFa inhibition of Surfactant Protein B protein expression"

Laboratory Assistant

Colorado Genetics Laboratory

2000-6 - 2001-7 · 1 yr 2 mos

Handled in take and processing of human samples Maintained blood cultures and isolation of white blood cells for cytogenetic analysis Maintained laboratory equipment and supplies ABSTRACTS Characterization of an Experimental Lubricant Solution for Dry Eye