edward sionov

research scientist

About

- Highly motivated researcher/scientist with broad knowledge and strong expertise in fields of molecular microbiology, mycology, mycotoxin research, drug development, animal models, investigation of drug resistance - Strong publication record in peer-reviewed journals - Excellent communication skills and teamwork ability - Experience of managing teams in collaborative research and development - Fluent in English, Russian, Hebrew

Country

israel

City

israel

Industry

research

Skill

in vitro, animal models, in vivo, immunofluorescence, molecular biology, western blotting, cell biology, confocal microscopy, protein expression, molecular cloning, fluorescence microscopy, cell, microbiology, qpcr, rt pcr, flow cytometry, cell culture, tissue culture, elisa, genotyping

Experience

postdoctoral fellow

department of clinical microbiology hadassah medical center the hebrew university

2005-8 - 2007-8 · 2 yrs 1 mo

Development of new antifungal agents; team supervisor for drug development

research fellow

national institutes of health

2012-5 - 2014-8 · 2 yrs 4 mos

Identification of Hsp90 in Cryptococcus neoformans and examination of Hsp90 inhibitors geldanamycin and it's novel water-soluble analog 17-DMAG In Vitro and In Vivo. Investigation of a novel immune therapy on murine model of cryptococcosis.

postdoctoral visiting fellow

national institutes of health

2007-8 - 2012-5 · 4 yrs 10 mos

Investigation of drug resistance in human pathogenic fungi: molecular characterization of adaptive azole resistance in Cryptococcus neoformans, a major cause of meningitis in immunocompromised patients

research scientist

agricultural research organization volcani center

2014-9 - Present · 12 yrs 1 mo

Mycotoxigenic fungi and mycotoxins Mycotoxins are low-molecular weight natural products produced as secondary metabolites by toxigenic filamentous fungi that contaminate food, the food chain, and represent a risk to human and animal health. When present in foods in at sufficiently high levels, these fungal metabolites can have a toxic effect that ranges from acute (liver or kidney deterioration), to chronic (liver cancer). In addition, the presence of mycotoxins in wide range of agricultural commodities is also an economic concern. A quarter of the world’s crops are estimated to be contaminated to some extent with mycotoxins. The increasing consumer demand for safe food is accompanied by the need for early, rapid and cost-effective analytical and molecular techniques capable of screening for the presence of mycotoxins and/or mycotoxigenic fungi, which would allow prevention of mycotoxin contamination of the human food supply and have a significant effect on public health.