Dr. Rajan Goel
Healthcare Innovator, Pharmacologist
About
Pharmaceutical industry researcher with proven track record in drug discovery and development, drug repurposing and translational research. Subject matter expert for the evaluation, development and due diligence of novel healthcare products and therapeutics.Versatile experience of leading team of scientists responsible for pre-clinical modeling of human disease including ex-vivo, in- vivo (animal models) efficacy, target-engagement, biomarkers assessment and safety pharmacology across different disease areas.Regulatory documentation to support Ph 1 and Ph 2 clinical development including Investigational New Drug Application (INDA) and related documents.Key contributor to out-licensing of three small molecules (alpha blocker for BPH, MALT1 inhibitor and MEK inhibitor for cancer) to three different global pharma companies. More than eight potential drug candidates entered in advance clinical development stages in India and abroad. Identification of differentiated clinical and potential drug candidates.Experience of working for different therapeutic areas viz. cardiovascular diseases, metabolic disorders, chronic pain, bone metabolism, chronic kidney disease, CNS disorders, oncology, immuno-oncology, autoimmune disorders, inflammation and urological complications.Evaluation, assessment and validation of novel discovery research targets. Exploring unmet medical needs in different therapeutic areas and disease indications.Added experience of working for women healthcare innovation and discovery research.Cross-functional execution of preclinical studies required for drug discovery and development including chemistry, analytical, in-vitro, in-vivo, pharmacodynamics, ADME, safety and clinical teams, enabling drug developmentExtensive experience of leveraging scientific opportunities, cross-functional leadership, strategy planning, implementation, knowledge management, project mentoring, resource optimization, talent identification and nurturing teams to ensure success.Planning and tracking annual budget and capital expenditure for the department and drive processes and systems to adhere to the planned budget.#opentowork #jobapportunity
India
Pune Division
Pharmaceuticals
Drug repurposing , Drug screening, Natural products , Leadership Mentoring, Corporate Leadership, Mentoring, Strategic Project Management, Medical Writing, Scientific Writing, Guest Lecturing, University Lecturing, Knowledge Management, Project Portfolio Management, Talent Management, Talent nurturing , Talent Identification, Portfolio Management, Educational Consulting, Non-clinical , Good Laboratory Practice (GLP)
Experience

Healthcare Innovator, Pharmacologist
Pharma Research Novel Drug Discovery Development & Healthcare Innovation
Pune District
Drug discovery & Repurposing, Translational Research, Small molecules , Herbals, Industry subject matter expert, Novel healthcare products, Novel medical therapeutics, women healthcare, Product driven research , Industry educator, Public-private partnership, Industry-academia interaction and collaboration, SME to CPCSEA, MoHFW, DST, DBT and ICMR. Professor of Practice. New experimental R&D labs designing including contaiment area.

Director - Preclinical Pharmacology/Discovery Biology , Drug Delepment.
Lupin Ltd. - NDDD R&D
● Out-licensing of two novel small molecules to global pharma companies viz. MALT1 inhibitor to Abbvie and MEK inhibitor to Boehringer Ingelheim ● INDA filing for more than eight potential drug candidates. ● INDA filing and defence for Ph1 approval of natural products for Psoriasis, Migraine and Asthma, by NCE route as per US FDA guidelines ● Discovery Research project planning, implementation and mentorship, ● Therapeutic area assessment and selection, ● Regulatory submissions for Novel drug candidate.development. ● Preclinical human disease simulation using transgenic, genetically mutant, surgically, chemically and diet induced in-vivo models. Establishing ex-vivo and in-vitro assay methods for better translational from bench to bed. ● Strategy implementation for novel product driven research, ● Competitive intelligence and analytics ● Research portfolio planning and management ● Designing and establishing state of the art R&D labs including contaiment facility ● Premature superannuation

Team Leader - Preclinical Pharmacology , Drug Discovery Development Research
New Delhi & Gurgaon India
● Out-licensing of novel small molecule RBx-2258 for BPH to Schwarz Pharma. ● INDA filing and regulatory documentation for two potential drug candidates. ● Preclinical in-vivo and in-vitro characterization, hit to lead optimization, clinical candidate identification Human disease modeling in preclinical experimental models. ● Discovery liability studies and general nonclinical pharmacology studies.
Education
Dr. Rajan Goel's Contact Information
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