Dr. Fatemeh Zahedipour
Senior Scientist @ CPTx
About
🔬 Scientist | Biotechnology | Cancer Immunotherapy | Nanotechnology & Drug DeliveryScientist with expertise in lipid nanoparticle (LNP) formulation and functionalization for nucleic acid therapeutics, focusing on targeted delivery strategies for DNA and mRNA-based immunotherapies. My work combines nanotechnology, gene editing, and immune cell engineering to advance next-generation therapies for cancer and immune-related diseases.My research experience includes the development of nanoliposomal peptide vaccines for solid tumor immunotherapy, as well as LNP-based delivery platforms for gene editing and T-cell–based therapies, including CAR-mRNA delivery to immune cells.I work in interdisciplinary environments integrating nanoparticle engineering, molecular biology, and translational research to develop innovative therapeutic platforms.🔹 Key Expertise• Lipid Nanoparticle (LNP) Formulation & Functionalization• Targeted Drug Delivery & Nucleic Acid Therapeutics• Cancer Immunotherapy & T-cell Therapies• Molecular & Cellular Biology• Nanomedicine & Translational ResearchI am always open to networking and collaborations in biotechnology, nanomedicine, and next-generation therapeutics.
Germany
Munich
Higher Education
Analytical Method Validation, Method Transfer, Bacterial Transformation, Expression Cloning, gene engine, Protein Purification, Chromatography, Facilitation, Communication, Analytical Skills, Troubleshooting, Problem Solving, Quality Control, Organization Skills, RNA in vitro transcription, Small Animal Models, PBMC isolation, Primary Cell Isolation, Cancer Genomics, Fluorescence Microscopy
Experience
Senior Scientist
CPTx
Munich
Scientist_ Formulation Functionalization
BioNTech SE
Mainz
Visiting Research Scientist
Universitätsklinikum Tübingen
Germany
Led a full technology transfer of a microfluidic-based mRNA-LNP synthesis pipeline and related analytical techniques to formulate CAR mRNA-LNPs for efficient mRNA transfection into primary and expanded NK cells to enhance their anti-leukemic effects. Proven expertise in CAR-mRNA in vitro transcription, formulation, and characterization of lipid nanoparticles for targeted CAR-mRNA delivery into primary NK cells.
Laboratory Scientist
Shahid Beheshti University of Medical Sciences
Demonstrating expertise in molecular biology methodologies, design and execute gene engineering, cloning, protein expression and purification projects, employing advanced techniques in genetic engineering.
Education
Mashhad University of Medical Sciences
Biotechnology
Thesis: Design and development of a nanoliposomal peptide-based vaccine containing VEGF-R2 peptides and MPL and evaluation of its immune and antitumor response in murine models of melanoma.
Shiraz University of Medical Sciences
Medical Biotechnology
Thesis: Development of flow cytometry-fluorescent in situ hybridization (Flow-FISH) method for detection of PML/RARa chromosomal translocation in acute promyelocytic leukemia cell line.
Dr. Fatemeh Zahedipour's Contact Information
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