Dong Shin Park

Scientist @ BioMarin Pharmaceutical Inc.

About

With over a decade of extensive research experience in human induced Pluripotent Stem Cells (iPSC), neuroscience, and immunology, I am a dedicated scientist focusing on the intricate interactions between neurons and glial cells in the brain. Currently a postdoctoral associate at MIT, I utilize human iPSCs and mouse models to investigate Alzheimer's disease and Down Syndrome. Previously, I conducted research as a PhD student and postdoctoral fellow at A*STAR in Singapore, studying the role of microglia in embryonic brains through in vitro brain organoids generated from human iPSCs. My track record includes numerous publications, patent, and awards, underscoring my scientific prowess and innovation. A collaborative and supportive team member, I thrive on working with diverse colleagues, mentors, and partners. My overarching aim is to advance knowledge and enhance human health outcomes through impactful research contributions.

Country

United States

City

San Francisco

Industry

Research

Skill

Teamwork, Team Leadership, Laboratory Skills, Research, Research Projects, Journals, Biology, Bioinformatics, Science, In Vivo, Manuscript

Experience

Scientist

BioMarin Pharmaceutical Inc.

2025-6 - Present · 1 yr 4 mos

United States

Postdoctoral Associate

Massachusetts Institute of Technology

2021-6 - 2025-5 · 4 yrs

United States

- Led a project team investigating sensory stimulation effects on both adult and embryonic brain of Down syndrome mouse model (Ts65Dn). - Developed a human iPSC-derived 3D in vitro brain model to study Alzheimer’s disease pathologies associated with the APOE4 genetic risk.

Postdoctoral Research Fellow

A*STAR - Agency for Science, Technology and Research

2020-1 - 2021-1 · 1 yr 1 mo

Singapore

-Led a collaborative project to characterize and validate the functions of iPSC-derived microglia in brain organoids. -Collaborated with scientists from another lab to develop a patented protocol for establishing iPSC-derived microglia and brain organoid co-culture systems. -Contributed as a team member to research investigating how the Zika virus affects brain development using microglia-sufficient brain organoids.

Young investigator PhD course participant

EMBL

2016-12 - 2016-12 · 1 mo

Heidelberg, Baden-Württemberg, Germany

-Participated in a comprehensive program focusing on presentation skills, manuscript writing, networking, and mentoring.

Graduate Research Assistant

A*STAR - Agency for Science, Technology and Research

2015-8 - 2016-4 · 9 mos

Singapore

-Contributed to generation of multiple iPSC cell lines from the fibroblasts of Alzheimer’s disease patients.

Research Assistant

Korea Advanced Institute of Science and Technology

2015-1 - 2015-7 · 7 mos

South Korea

-Cloned genes into E.coli to produce target proteins. -Purified proteins via size exclusion and high affinity chromatography. -Utilized Transmission Electron Microscopy (TEM) and Cryo-EM for protein structure analysis.