derya shimshek

investigator and lab head

About

* Neuroscience expert (drug discovery and basic research) * Expert in target discovery, target validation, pharmacokinetics / pharmacodynamics and in assay development for measuring target and pathway engagement * Establishment of new in vivo models to study molecular pathways of proteinopathies in Parkinson`s and Huntington`s disease * Execution and evaluation of in vivo therapeutic efficacy studies * In-depth knowledge of molecular genetics, biochemistry, histology and behavior * Development of preclinical and clinical biomarkers and evaluation of proof-of-concept trials * Project Team Leader, key member of several preclinical drug discovery teams and extensive international academic collaborations; several important and groundbreaking publications * Efficient and effective project management; inclusive leadership style * Working independently with personnel responsibilities embedded in a motivated multidisciplinary and multicultural team * Approaching challenging tasks in a foresighted, creative, flexible and systematic fashion

Country

switzerland

City

basel

Industry

pharmaceuticals

Skill

animal physiology, histopathology, neuropathology, therapeutic antibodies, qpcr, aggregation, genotyping, cell biology, elisa, western blotting, neurodegeneration, neuroscience, aav, antibodies, confocal microscopy, capillary electrophoresis, in situ hybridization, behavior, immunofluorescence, neurodegenerative diseases, tr fret, drug discovery, molecular biology, cre/tta, histology, transgenics, immunohistochemistry, neuropharmacology, neurodegenerative, pharmacokinetics, viral vectors, pharmacodynamics, pharmacology, immunoprecipitation, molecular cloning, alpha synuclein, lrrk2, robotics, biochemistry, neurodegenerative disease, physiology, biomarkers, protein chemistry, colony maintenance, microscopy, northern blotting, capillary

Experience

investigator and lab head

novartis

2006-1 - Present · 20 yrs 9 mos

Novartis provides healthcare solutions that improve and extend people's lives. We use science-based innovation to address some of society's most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible.Our company is focused on industry-leading divisions with innovation power and global scale: pharmaceuticals, eye care and generic medicinesNovartis is headquartered in Basel, Switzerland. Novartis Group companies employ approximately 120,000 associates and its products are available in more than 180 countries around the world.See our community guidelines: https://www.novartis.com/sites/www.novartis.com/files/linkedin-community-guidelines.pdf