Denis Haché

Oversee Staff Scientists in the conduct of their studies.

- Supervise, train and coach a team in continuos process improvement. - Communicate the quality goals, performance goals and health and safety goals to the team. - Maintain a optimal productivity and efficiency by using key peformance indicators. - Ensure the integrity of instrument preventive maintenace and repairs. - Responsible of the recrutment and the daily resource planning. - Manage the operational budget.

- Supervise, train and coach a team in continuos process improvement. - Communicate the quality goals, performance goals and health and safety goals to the team. - Maintain a optimal productivity and efficiency by using key peformance indicators. - Ensure the integrity of studies and meet the requirements of regulatory agencies. - Responsible of the recrutment and the daily resource planning. - Manage the operational budget.

Overview the Quality System in the Chemistry, Incoming QC and Microbiology laboratories. - Compare the Standard Testing Methods against relevant pharmacopeias and approved submitted methods. - Establish and implement basic procedures, training requirements, programs, and techniques consistent with company policies and standards to achieve quality control objectives. - Participate in the resolution of process deviations and product failures by providing investigation reports sufficient to aid in the diagnosis and goods. - Provide leadership and technical support of quality objectives to staff and outside departments.

Overview the Quality System in the laboratories. - Compare the Standard Testing Methods against releveant pharmacopeias and approved submitted methods. - Establish and implement basic procedures, training requirements, programs, and techniques consistent with company policies and standards to achieve quality control objectives. - Participate in the resolution of process deviations and product failures by providing investigation reports sufficient to aid in the diagnosis and goods. - Provide leadership and technical support of quality objectives to staff and outside departments.

Overview the Quality System in the laboratories. - Compare the Standard Testing Methods against releveant pharmacopeias and approved submitted methods. - Establish and implement basic procedures, training requirements, programs, and techniques consistent with company policies and standards to achieve quality control objectives. - Participate in the resolution of process deviations and product failures by providing investigation reports sufficient to aid in the diagnosis and goods. - Provide leadership and technical support of quality objectives to staff and outside departments.

- Overview the Quality System in the laboratories. - Compare the Standard Testing Methods against releveant pharmacopeias and approved submitted methods. - Establish and implement basic procedures, training requirements, programs, and techniques consistent with company policies and standards to achieve quality control objectives. - Participate in the resolution of process deviations and product failures by providing investigation reports sufficient to aid in the diagnosis and goods. - Provide leadership and technical support of quality objectives to staff and outside departments.

- Participate in the production quality documents from the division. - Make travel reservation and complete expenses account for the manager. - Do filing and updating records manager in accordance with the procedures for information management at the beginning of each month.

- Plan and distribute assignment tasks to a team of 15 enumerators. - Perform efficient client service to the respondents. - Answer to the public service request either by phone or by a visit - Control the costs related to the different tasks performed by the enumerators on the field

- Plan and control the budget of the different laboratories: Analytical, Bioanalytical, Clinical Pathology, Immunology and Pharmacy. - Coordinate with the different department heads the preparation and analysis of samples according to SOP’s, protocols and Good Laboratory Practices (GLP’s) ; - Approve Analytical, Bioanalytical and Immunology reports, method SOP, SOP deviations and investigation reports; - Promote the different laboratory services; - Participate in client and regulatory agency audits

- Evaluate equipment and instruments necessary for the new Analytical and Bioanalytical services; - Put in place procedures and SOPs for the new services; - Hire qualified personnel for the Analytical and Bioanalytical laboratories; - Control validation activities for instrument and software (electronic compliance) ; - Prepare and approve quotes sent to sponsors for method validation and sample analysis studies; - Plan sample analysis (dosing formulation and biologic samples) according to protocols, SOP’s and GLP’s; - Approve Analytical and Bioanalytical reports, method SOP, SOP deviations and investigation reports; - Participate in client and regulatory agency audits.

- Evaluate daily activities of the analytical team : validation and sample analysis of dosing formulation and biological samples; - Evaluate the quality and competency of the Analytcal staff members; - Evaluate the global quality and supporting documentation of the analyses.

- Supervise a team of professionals and technicians ; - Supervise the work of quality inspectors of the division ; - Control the activities of instrument and software validation for the division (electronic compliance) ; - Plan and control the budget for the bioanalytical sector ; - Participate in revision of divisional and corporate standard operating procedures (SOP) to make sure that they are compliant to the different regulatory agencies ; - Approve bioanalytical reports, protocol and SOP deviations, bioanalytical method SOP and investigation reports ; - Participate in client and regulatory agency audits ; - Assist to operation and integration committee.

- Supervise a team of project coordinators and technicians ; - Plan the work of project coordinators and laboratory technicians and as well the analytical instrument utilization (LC/MS/MS, LC/MS, GC/MS, GC and HPLC) ; - Participate to the preparation and control of the bioanalytical budget ; - Collaborate to the revision of divisional and corporate standard operating procedures (SOP) to make sure that they are compliant to the different regulatory agencies ; - Approve protocol and SOP deviations ; - Communicate with internal and external clients.

- Supervise a team of assistant supervisors and technicians ; - Schedule sample analysis according to SOP, protocols and Good Laboratory Practices (GLP) ; - Optimize the utilization of analytical instruments (LC/MS/MS, GC/MS, GC and HPLC) ; - Interact with other services and divisions of the company and with clients ; - Hire and evaluate personnel

- Supervise a team of scientist reviewers and laboratory technicians ; - Schedule sample analysis and bioanalytical method validation of LC/MS and LC/MS/MS projects according to SOP, protocols and Good Laboratory Practices (GLP). - Manage all bioanalytical projects using automated on-line extraction in order to reduce the client timelines.