Dengchen Yang

Research Focus: AI-empowered drug discovery and interdisciplinary biopharmaceutical research Core Responsibilities & Achievements: Lead research projects on AI-driven design of viral small-molecule inhibitors, targeting key viral proteins including SARS-CoV-2 and RSV Develop innovative computational frameworks integrating machine learning with structural biology for rational drug design Design and optimize novel vaccine adjuvants and intelligent delivery systems using computational approaches Manage multiple research collaborations, coordinating between computational and experimental teams Author and co-author high-impact research papers and reviews in peer-reviewed journals

Research Focus: Computational Physics and Soft Matter Physics Key Research Achievements: Developed novel computational methods for protein crystal structure determination using direct methods Rewrote and optimized core algorithms in Fortran to solve phase ambiguity in protein crystallography Led the design and development of a clip-on cryo-sample preparator for Transmission Electron Microscopy, rated as an Outstanding Project Conducted comprehensive technical research on Cryo-Electron Microscopy (Cryo-EM), Cryo-Electron Tomography (Cryo-ET), and synchrotron radiation applications Authored and co-authored multiple high-impact publications in renowned scientific journals

Research Focus: Design and development of high-performance organic photovoltaic materials. Key Contributions: Designed and synthesized novel polymer donors and A-D-A type small-molecule acceptors for organic solar cells, achieving enhanced photovoltaic efficiency. Fabricated and optimized organic solar cells (OSCs), performing comprehensive device testing including J-V characterization and external quantum efficiency (EQE) measurements. Conducted in-depth morphological and photophysical analysis using atomic force microscopy (AFM), UV-Vis spectroscopy, and steady-state/transient photoluminescence spectroscopy. Applied computational chemistry methods, including Density Functional Theory (DFT), to study molecular electronic structures and establish structure-property relationships. Published multiple first-author papers in high-impact journals and collaborated on interdisciplinary projects.

Research Focus: Design and synthesis of helicene-based fluorescent probes for molecular recognition Key Contributions: Multi-step Organic Synthesis: Expertise in the design and synthesis of complex architectures, including helicenes and fluorescent molecular probes. Supramolecular Chemistry: Proficient in studying molecular recognition and self-assembly via NMR titration and fluorescence spectroscopy. Advanced Structural Characterization: Skilled in comprehensive molecular structure elucidation using NMR (1H, 13C, 2D), HRMS, and FT-IR. Fluorometric Analysis: Applied steady-state fluorescence spectroscopy for developing chemosensors and investigating photophysical properties. Purification & Analysis: Experienced in compound purification using column chromatography and reaction monitoring with TLC/UV-Vis spectroscopy.

Research Focus: New Energy and Nanomaterials (Hydrogen Production and Storage) Thesis Project: "Hydrogen Energy Preparation and Storage" Awarded "Outstanding Graduation Thesis" (top 3 in major) Key Research Contributions: Conducted innovative research on hydrogen generation using magnesium-based nanomaterials Investigated the catalytic effects of cations on hydrogen production efficiency Co-authored research findings published in Chemical Communications Mastered advanced material synthesis and characterization techniques

Academic Focus: Strategic Management, Marketing, Organizational Behavior, Financial Accounting, and Business Economics Undergraduate Thesis: "Market Forecast and Analysis of China's Rare Earth Resources" Advisor: Prof. Jin Hong, Expert in Risk Management Key Achievements: Completed a comprehensive business curriculum alongside primary engineering degree requirements. Developed cross-functional expertise in business strategy and management principles. Applied quantitative analysis and risk management frameworks to forecast trends in a strategic commodity market.

Academic Focus: Fine Chemical Engineering & New Energy Materials Key Achievements: Conducted graduation project at Peking University on "Hydrogen Energy Preparation and Storage," awarded Outstanding Graduation Thesis (top 3 in major) Published 1 SCI paper in Chemical Communications as co-author on hydrogen generation research Led 1 national-level innovation project: "Electrocatalytic Detection of Clenbuterol using Metalloporphyrin-Silicotungstate Probes" (successfully concluded) Participated in 2 university-level innovation projects on silicotungstate-modified electrodes, receiving: • First Prize in Beijing College Chemistry Experiment Competition • Excellent Award in University Student Innovation Project

Program Focus: Cross-disciplinary Integration of Engineering Management, Systems Thinking, and Technological Innovation Key Learning Outcomes: Developed frameworks for managing projects spanning multiple engineering disciplines Acquired skills to bridge technical communication gaps between different engineering fields Established methodologies for integrating diverse technical requirements and constraints Enhanced ability to coordinate cross-functional teams in complex technical environments Practical Applications: Successfully applied interdisciplinary management approaches to coordinate research spanning chemistry, physics, and biology Implemented systems thinking in managing the cryo-TEM sample preparation project Utilized cross-disciplinary coordination skills in AI-driven drug discovery initiatives Certification: Certified Project Management Associate (IPMA Level D) UNEP Leadership Training in Sustainable Consumption