David Waterman

• Leading IND enabling studies for multiple LNP programs, ensuring timely project delivery. • Author of comprehensive IND sections and supporting documents, enhancing regulatory compliance. • Managing in-house vivarium operations, optimizing logistics and scheduling for efficient data generation.

-Research lead for LNP liver program in development -Authored preIND briefing book, helping to design regulatory strategy -Design and leading IND-enabling studies

- Biology lead for early project team using LNP to deliver gene editing RNA cargo to the liver - Participated in FDA INTERACT preparation - Developed non-human primate experimental strategy

- Led early discovery program from initial strategy to proof-of-concept. - Developed & optimized screening methodology to improve throughput & enable technological improvements.

- Drove early hit finding strategy resulting in lead identification for top company indication in 4 months. - Established pipelines to create reagents by PCR & cloning and analyze gene editing data by NGS - Generated new IP - Assisted in building teams, interviewing and hiring first 100 people

GreenLabs Recycling collects and recycles plastic used in research labs across Massachusetts. I help set the overall company strategy & goals, quarterly budgets, participate in hiring and help ensure our customers have the very best, transparent service to achieve their sustainability goals.

In vivo and in vitro cancer biology, DNA repair, replication stress, aneuploidy.

Examining the ubiquitin-proteasome system in health and disease.