Christopher Aluise
Director, Toxicology @ Rapport Therapeutics
About
Toxicology project leader with 10 years of industry experience supporting both small and large molecule modalities as well as oligonucleotide-based therapies with a focus on neuroscience and pain therapeutic areas. Experience includes support of teams throughout all phases of drug development, from pre-portfolio entry to late Phase 3 clinical trials. Lead author of toxicology-relevant sections of regulatory documents such as Investigational New Drug Applications (INDs), Biologics License Application (BLA), New Drug Application (NDA), and Type B/C briefing documents. Experience with health authorities includes representing teams in both face-to-face meetings and teleconferences. Subject matter expert in drug abuse liability. Toxicology study experience includes design, oversight, and data interpretation/communication from studies assessing safety pharmacology, general toxicology, abuse liability, developmental and reproductive toxicology, combination toxicology, and carcinogenicity. Strong basic science background with focus on oxidative stress, cell signaling, and chemical biology.
United States
Greater Indianapolis
Biotechnology
Pharmacology, Biochemistry, Neuroscience, Cell Culture, Cell Biology, Molecular Biology, Regulatory Affairs, Toxicology, Drug Abuse liability, Chemical Biology
Experience
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