Christopher Aluise

Christopher Aluise

Director, Toxicology @ Rapport Therapeutics

About

Toxicology project leader with 10 years of industry experience supporting both small and large molecule modalities as well as oligonucleotide-based therapies with a focus on neuroscience and pain therapeutic areas. Experience includes support of teams throughout all phases of drug development, from pre-portfolio entry to late Phase 3 clinical trials. Lead author of toxicology-relevant sections of regulatory documents such as Investigational New Drug Applications (INDs), Biologics License Application (BLA), New Drug Application (NDA), and Type B/C briefing documents. Experience with health authorities includes representing teams in both face-to-face meetings and teleconferences. Subject matter expert in drug abuse liability. Toxicology study experience includes design, oversight, and data interpretation/communication from studies assessing safety pharmacology, general toxicology, abuse liability, developmental and reproductive toxicology, combination toxicology, and carcinogenicity. Strong basic science background with focus on oxidative stress, cell signaling, and chemical biology.

Country

United States

City

Greater Indianapolis

Industry

Biotechnology

Skill

Pharmacology, Biochemistry, Neuroscience, Cell Culture, Cell Biology, Molecular Biology, Regulatory Affairs, Toxicology, Drug Abuse liability, Chemical Biology

Experience

Rapport Therapeutics

Director, Toxicology

Rapport Therapeutics

LinkedIn
2025 - Present · 1 yr
Karuna Therapeutics

Director, Toxicology

Karuna Therapeutics

LinkedIn
2021-11 - Present · 4 yrs 11 mos
Eli Lilly and Company

Principal Research Scientist

Eli Lilly and Company

LinkedIn
2020-6 - 2021-11 · 1 yr 6 mos
Eli Lilly and Company

Senior Research Scientist - Toxicology

Eli Lilly and Company

LinkedIn
2016-10 - 2020-6 · 3 yrs 9 mos
Eli Lilly and Company

Research Scientist

Eli Lilly and Company

LinkedIn
2014-3 - 2016-10 · 2 yrs 8 mos

Indianapolis, Indiana Area

Vanderbilt University Medical Center

Postdoctoral Fellow, Biochemistry and Pharmacology

Vanderbilt University Medical Center

LinkedIn
2010-2 - 2014-1 · 4 yrs

Elucidating the induction of the heat shock response by products of oxidative stress.

Education

University of Kentucky

University of Kentucky

LinkedIn

Biological Chemistry (Neuroscience focus)

2005 - 2010 · 5 yrs
Miami University

Miami University

LinkedIn

Chemistry

2000 - 2005 · 5 yrs

Christopher Aluise's Contact Information

Email

******@***.com

Phone

(**) *** ****

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