Chetan Chana, PhD

* Protein purification, X-ray crystallography and high-throughput assay development to support drug discovery

Supervised by Dr. Frank Sicheri * Evaluated a novel molecular glue I discovered in my PhD studies and published the findings

Supervised by Dr. Frank Sicheri * Purified 15+ different proteins and protein complexes, determined 20+ structures by X-crystallography and 2 structures by cryo-EM * Led a drug discovery campaign against an E3 ligase, yielding small molecule candidates for protein inhibition and/or targeted protein degradation * Co-wrote 3 first-author publications * Presented my findings as oral or poster presentations at 15+ scientific gatherings with 30 to 150 participants

* Directly supervised and trained an undergraduate student with no initial research experience for over a year, ultimately leading them to contribute scientifically to research projects that yielded co-authorship on two publications

Department of Molecular Genetics (course code: MMG1001) Course instructors: Dr. Anne-Claude Gingras (2019-2022) & Ji-Young Youn (2023) * Beginning in its inaugural year, designed assignments and led weekly tutorial sessions overseeing 14-16 students, with discussions of staple techniques used to study proteins and modern technological advances, resulting in the renewal of my contract for 4 consecutive years

* Recruited senior investigators and trainee speakers for institute-wide bi-weekly oral presentations * Organized the seminar space, coordinated lunch for attendees and introduced invited speakers

* Purified, crystallized, and determined the structure of proprietary oncogenic protein targets bound to small molecule inhibitors

Honor's Specialization in Biochemistry and Cell Biology