Charlie C.
Consultant
About
Passionate and curious medicinal chemist with fifteen years of experience in small, medium and large biotech/pharma companies. • Key contributor to two Tubulysin based clinical antibody drug conjugate programs for cancer. • Experience as program chemistry lead in cross-functional team. • Excellent lab skills and ability to make good use of modern equipment in a medicinal chemistry lab. • Comfortable with designing and synthesizing biologically active small molecules ranging from heterocycles to natural products and cyclic dinucleotides. • Expertise in structure-based drug design to address program challenges (potency, selectivity, metabolic stability, hERG, CYP, PK, in-vitro and in-vivo pharmacology, intellectual property (IP)). • Extensive use of x-ray structure, Livedesign, Mastro and Lead discovery for CADD and visualization. • Experience with effective utilization of CRO to support chemistry needs.
United States
Sunnyvale
Biotechnology
Medicinal Chemistry, Antibody Drug Conjugates, Small Molecules Drug Discovery, Pharmaceutical Industry, Biotechnology, Pharmacology, High-Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), Nuclear Magnetic Resonance (NMR), Heterocycle synthesis, SAR development, Lead Optimisation, Payload Synthesis, Linker Synthesis, Pharmacokinetics, immunomodulator, Patent Preparation, X-Ray, Peptide synthesizer, Maestro
Experience

Consultant
Consultant for Whitehawk Therapeutics, from 2025 - Current Providing subject matter expertise in the area of Antibody-Drug Conjugate development, manufacture and testing. Helped with two successful IND applications that received FDA clearance

Principal Scientist
Project chemistry lead for small molecule CNS drug, activities: hit generation through virtual screening and HTS, hit expansion, lead generation and optimization, formulation and execution of medicinal chemistry strategy, management of CRO and assembling of information for IP filings.

Director of Medicinal Chemistry
CS-Bay Therapeutics
Newark, California, United States
• Antibody-Drug-Conjugate R&D for Cancer

Scientist II
Medarex (Acquired by BMS in May 2009)
Sunnyvale, CA
• Key contributor to two Tubulysin-based clinical ADC programs.
Charlie C.'s Contact Information
Phone
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