Charis W.

1. Clinical development activities 1) For new product - As one of key partners responsible for CFDI inspection of phase I+III trial: on-site response to CFDI inspectors’ questions via fully grasping all medical aspects of the trail; be familiar with what CFDI focus on in raw data quality, patient safety et al; prepare for written response to CFDI key findings by discussing with global team and PI; prepare presentation slides for CFDI panel meeting 2) For PMS - Play a key role in 1 PMS initiation (involving 60 AP-sites) and 2 PMS closed-out, including study design, PI communication, protocol writing, sites selection, CRO communication, investigator meeting preparation, result presentation at satellite meeting 3) For IIT - Successfully achieved China IIT approvals from global R&D center with high quality and minimized approval time by effective communication with headquarter, strong partnership with investigators and fast learning capability (technology outside my specialty). Achieved 3 out of 6 China IIT approvals and set the shortest approval record, which changed the approval-time-delayed situation, and won customer confidence of further collaboration. - Interpret trials’ product value to cross-function team and smooth the cooperation with related stakeholders. - Enhance local data generation/IIT through continuous discussion with intending KOLs to inspire strategy fit ideas.3 proposals were in preparation. 2. Innovatively provide thoughtful medical solution to business partners to deal with key product issues - Specific insights collection and experience exchange by field visits - Set up new unconventional KOL network and drive new medical association establishment based on specific field sights - Produce videos for good clinical experience sharing 3. Gain crisis management experience by dealing with negative opinion of EU scientific committee Disease area: radiology & intervention incl. cardiology, neurology, oncology etc.

1 Ensure top level medical contribution to internal and external customers for adding product's vigor - Generated novel in-depth scientific slides for scientific meeting. e.g. “almost alike by nature, quite different by practice” clarified our product more suitable for Asian related gene mutations with specific bio-activation ways， “benefit from ischemic preconditioning” et al. 2 Clinical development activities - Fully involved in third party study by study design, CRFs design, investigator meeting, tracking. The result was accepted by 2016 Euro Heart Congress. - Partnership with KOL in IITs using the platform of research grant cooperated with China medical doctor association. e.g. “Nitrates optimization strategies evaluation in AHF patients” which provided a more effective alternative application method for product. 3 Generate digital medical channel cooperated with DXY - High quality contents contribution & topic design: product centennial history et al - Good digital communication tool for commercial team which is still in use 4 Build partner relationship with KOL and reginal commercial team: - Exchange new medical information and insights with KOL through organizing regional AB meeting/ regional seminars and field visits - Provided KOL insights and medical input to commercial team, and developed sale force's medical capability through training and Q&A Disease area: cardiology, emergency medicine