Ce Wang
Senior Scientist II @ AbbVie
About
• Cell biologist with 6-year industry experience in broad topics. • PhD in Molecular, Cellular and Developmental Biology with advanced training and extensive experience in cell biology, molecular biology, immunology, neuroscience, immuno-oncology, oncology, and drug discovery especially targeted protein degradation. • Excellent written and verbal communication skills. • Extremely self‐motivated, well‐organized, multi‐tasking and fast learning. • Excellent collaborator and leader across cross-functional teams
United States
Cambridge
Research
Antibody Discovery, Cross-functional Team Leadership, Immunology, Targeted Protein Degradation, Mammalian Cell Culture, Cell Biology, Molecular Biology, Confocal Microscopy, Super-resolution Microscopy, Flow Cytometry, Biochemistry, Animal Biology, Neurodegeneration, Neuroscience
Experience
Senior Scientist II
AbbVie
Cambridge, Massachusetts, United States
Led antibody discovery and targeted protein degradation (TPD) initiatives as an early member of AbbVie’s immunology group; advanced novel antibody-based modalities including mAbs, bispecifics, multispecifics, ADCs, and antibody-siRNA conjugates through cross-functional collaboration, in vitro/in vivo model development, and live-cell/ high-content imaging assays for candidate characterization and optimization.
Senior Scientist I
AbbVie
Cambridge, Massachusetts, United States
targeted protein degradation
Postdoctoral Fellow
AbbVie
Worcester, Massachusetts, United States
Immunology Antibody Drug Conjugates (iADC) team Identified antibody characteristics that drive efficient lysosomal internalization of antibody-drug conjugates (ADCs). Published in Science Translational Medicine.
Postdoctoral Research Associate
University of Michigan
Ann Arbor, Michigan, United States
Graduate Research Assistant (Professor Haoxing Xu lab)
University of Michigan
Ann Arbor
• Explored novel lysosomal ion channels and their functions (e.g. pH homeostasis, autophagy, and stress response); discovered small-molecule therapies via high-throughput screening targeting lysosomal dysfunction in neurodegenerative diseases and lysosomal storage diseases. • Co-first author on landmark Cell publication (2022) revealing TMEM175 as a proton-activated proton channel in lysosomes with therapeutic potential for Parkinson’s disease; work featured in major national and international media outlets. • Co-authored high-impact publications: PNAS (2020) on lysosomal osmoregulation/stress survival; Science Advances (2020) on Ca2+ channel activation in muscular dystrophy models.
Graduate Student Instructor
University of Michigan
Ann Arbor
Biology 172-Introductory Biology
Graduate Student Instructor
University of Michigan
Ann Arbor, MI
MCDB 306-Genetics Lab
Education
University of Michigan
Molecular, Cellular and Developmental Biology
Ce Wang's Contact Information
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