Caroline Winn, DVM, MS, DACLAM

- Lead animal care and use program for 27,000 sq ft rodent vivarium supporting cell, gene, and small molecule therapies, including budget, equipment, and staffing management - Provide veterinary leadership for in vivo pharmacology programs, including study design, veterinary consultation, and CRO oversight - Conduct global risk assessments, site visits, veterinary consultations, and external vendor evaluations to align welfare and compliance standards - Oversee veterinary, technical, and operations team; direct program development, health monitoring, and biosecurity - Direct and approve departmental resources, personnel, outsourced contracts, budget proposals and allocations - Advance educational platforms and hands-on training programs for researchers and technical staff

- Interim Attending Veterinarian; led Boston site animal care program / member of San Diego site IACUC - Developed cross-site training programs, regulatory readiness, and AAALAC compliance documentation - Led external facility audits and vendor assessments, aligning outsourced activities with internal standards

- Serving a leadership role in delivering clinical veterinary medicine and input to research projects in support of the company portfolio; veterinary direction provided to veterinary technicians and husbandry staff; oversee veterinary care and husbandry for a variety of human disease rodent models - Operate on site Leadership Team contributing to division initiatives, projects and operations - External vendor relations and collaborations to support studies and optimize transgenic and specialized models - Design, lead and conduct in vivo studies geared towards refining preclinical models and operational management - Management of direct reports- veterinary technicians and specialized research support scientists - Support continued compliance as specified in applicable local regulations, codes and guidelines; consult on research animal proposals submitted for IACUC review, participate in IACUC meetings, AAALAC Program Description development & maintenance of accreditation status, conduct of internal audits, and other inspections, including vendor audits - Lead initiative on rodent-free sentinel health monitoring, oversee the biosecurity and health monitoring program including maintenance of specific opportunistic pathogen-free Transgenics Core, site externship and outreach program for students and residents, and enrichment program - Consult on animal model development, interacting with colleagues to understand research needs - Develop, update, and implement processes, policies and standard operation procedures for facility functions and animal care including site bioburden and sanitization review and training documents

Clinical Responsibilities: - Lead veterinarian for three rodent and small animal facilities (~41,000 ft2), rodent neurobehavioral core, and four aquatic satellite facilities; provided preventative health care, medical workup and surgical treatment for a colony of macaques - Provided clinical diagnostic, triage, care, and treatment for animals used in research, including after-hours, weekend and holiday on-call support - Ensured and maintained the health status of the animal colonies through oversight of preventative health, sentinel programs & vendor surveillance, and import/export Regulatory Responsibilities: - Veterinary member of the IACUC, including consulting with researchers and the IACUC Chair on protocols, policy, and procedure development in compliance with applicable laws and regulations - Protocol pre-review, assisted researchers in protocol development, and post-approval monitoring - Supported maintenance of AAALAC accreditation, editing program description & assisting site visit Management Responsibilities: - Worked closely with and provided guidance to veterinary technical & animal care team - Wrote, reviewed, and updated SOPs in animal care and use, including husbandry, health surveillance, anesthesia and analgesia, and surgery - Trained investigators in the humane care and use of laboratory animals. Regularly collaborated and consulted to support study design, refinements, and research objectives

Postdoctoral Training & Clinical Experience: - Engaged in rotations focused on small, large, and aquatic medicine and surgery, clinical and anatomic pathology, health monitoring programs, training, facility management, and genetics, including 3-month rotation with Transgenics Core - Provided wellness, preventive healthcare, quarterly round-up & quarantine exams for an institution with over 100 macaques and 190 New World primates; routine and emergent care for rodents, swine, rabbits, ferrets, aquatic and avian species - Responsible for veterinary coverage of rodent health issues and investigator consultation in a 10,000 rodent cage neurobehavioral research facility - Ex officio member of the IACUC, protocol reviewer, participant in USDA & AAALAC visits and regulatory inspection/site visits, assuring compliance with all federal, state, and voluntary animal welfare laws and regulations; maintenance and revision of IACUC policies and SOPs, with lead role in developing rodent behavioral testing guidelines and fluid regulation policies for marmosets - Participated in a rotating after-hours/weekends/holidays on-call schedule - Delivered formal lectures concerning laboratory animal medicine and use in research, attended weekly seminars, clinical and pathology review, journal review, and directed a weekly ACLAM Boards Review for residents and students Postdoctoral Research Projects: - Effects of acute Helicobacter pylori infection in a hippocampal-specific mouse model of iron deficiency - The neurobehavioral impact of chronic H. pylori infection and iron deficiency - Investigating water intake of the common marmoset in the laboratory setting and establishing water regulation guidelines and recommendations for training - Isolation & molecular characterization of Group B Streptococcus from laboratory Long-Evans rats (Rattus norvegicus) with and without invasive disease

- Small animal and exotics general practice, performing preventive and wellness exams, illness and emergency visits, diagnostics, and elective surgeries - Managed and supervised veterinary technicians and front desk staff

Technical support and occasional primary case responsibility at a student-run veterinary clinic providing subsidized veterinary care within Central Massachusetts’ underserved communities. Performed routine canine and feline wellness exams, including routine parasite screening and selecting appropriate prevention. Provided treatment for common urgent care situations, including severe otitis externa, vomiting, diarrhea, and urinary tract infections and diagnostic services including blood tests and radiology.

Prepared for and observed surgeries, assumed veterinary technician duties such as bandaging, testing for intestinal parasites, heartworm and other diagnostic tests. Developed communication skills and worked efficiently as member of veterinary medical team.

Hands-on care of exotic species including peccaries, raccoons, parrots, owls, kinkajous, and crocodiles. Assisted in tours on wildlife conservation and endemic species. Improved Spanish communication skills.

Magna Cum Laude Sullivan Scholar Wake Forest University Abroad Scholarship