Carlo Borghesi

The Incubator is an innovation team of 25+ cross-functional employees divided into 6 streams, transforming BI beyond traditional pharma into the customer-centric healthcare solutions provider of tomorrow * Note: Incubator role is on top of core job responsibilities in Medical Affairs TPS leverages platform-based technology to address healthcare gaps, and is 1 of 6 Incubator streams: • Lead 3 member team through ideation, planning, developing, and execution of innovative healthcare projects • Current projects include an immersive gamification platform for Med Ed, a tech/healthcare trend scanning AI platform, and implementation of an external collaboration tracker platform for BI colleagues • Support Incubator leadership with additional special projects as required

Integration and support for Medical Affairs and Integrated Customer Engagement (ICE) activities: • Support all Therapeutic Areas with multi-channel campaign development to deliver dynamic digital/traditional channel medical content (e.g. e-Med Affairs websites, Med Ed platforms, etc.) • Continually iterate and improve medical content and channel usage based upon understanding of customer response and evolving needs and tools • Participate in assessment of novel media and digital partnerships to enhance digital strategies and customer engagement within Medical Affairs (e.g. virtual adboards) • Assist agency/partner alignment and coordination to support design of the digital content, and, ultimately, better customer experience • Assemble Medical Affairs operational, strategic data and metrics (i.e. monthly & campaign metrics capture for digital and Face-to-Face Medical Affairs activities for Therapeutic Area Directors, MSL Leads and MA Education & Operations Lead project management of Investigator Initiator Studies (IIS) across all Therapeutic Areas • Coordination of activities between Investigator, Local and Global Medical Teams through the lifecycle of IIS, including receipt, review, approval and release, and study closure • Administer development of legally sound contracts in accordance with assigned budget • Track IIS progress and receipt of deliverables through documentation in all required IIS management and documentation systems • Coordination of activities between Investigator, Local, and Global Pharmacovigilance and management of related safety data exchange activities and associated records

The Incubator is an innovation team of 25+ cross-functional employees divided into 6 streams, transforming BI beyond traditional pharma into the customer-centric healthcare solutions provider of tomorrow * Note: Incubator role is on top of core job responsibilities in Medical Affairs Signal Team is the think-tank/culture change driver of the Incubator, and is 1 of 6 Incubator streams: • Lead team of 8 cross-functional BICL colleagues • Detect emerging and disruptive tech trends in healthcare before they reach mainstream • Focus strategically but not exclusively on AI, VR/AR, Smart Cities, Internet of Things, Blockchain, and Social Media to identify customer-centric business opportunities • Inspire colleagues and leadership to act on promising opportunities with agility • Manage vendor to teach innovation skills and drive mindset shift for Incubator colleagues; negotiate services and pricing in line with Incubator leadership objectives and budget • Present team progress on objectives to all Incubator members and leadership • Network and liaise with technology experts across Canada • Support Incubator leadership with special projects as required

Use digital and scientific acumen to support strategic initiatives by MA: • Review/localize digital medical materials for MSLs to engage HCPs • Build, organize, maintain user-friendly portal for MSL access to digital medical materials • Perform literature searches to support MA or cross-functional colleagues Complete special projects as needed for Medical and other departments: • Created 2 Medical/Commercial compliance documents used by field-based colleagues • Identified and utilized relevant Health Canada, PAAB, IMC guidelines • Coordinated vendor and sales reps to recruit 70 physicians for CARD program in BC • Presented BICL internship opportunities to graduate students and screened applicant CVs Use project management and business acumen to help drive digitization of MA Co-team lead of Exec-approved Medical Information Facebook Pilot: • Develop first-in-industry, user-friendly customer solution despite regulatory complexity (identified/utilized relevant Health Canada, PAAB, IMC guidelines) • Improve connectivity of customers and patients to BI across all Therapeutic Areas • Design and launch communication strategy to engage HCPs and patients • Support pilot’s expansion to Animal Health, based on insights gained from metrics

The MBiotech Program is a 24 month, course-based professional degree program offered through the Institute for Management & Innovation at the University of Toronto Mississauga. The program incorporates both science and business courses with 8 to 12 months of work experience in industry. The carefully selected combination of courses, coupled with relevant industry experience and a strong focus on teamwork, provides graduates with a truly interdisciplinary educational experience at a world-renowned university

Fulfilled the simultaneous demands of several parties in a 400-guest capacity restaurant Engaged and conversed regularly with a diversity of international customers in the heart of the Niagara Falls tourist district Upsold menu items by enticing the customer with higher margin product offerings when appropriate Supported cross-functional team efforts of over 100 daily employees from various departments to ensure high customer satisfaction was consistently achieved

Administered research measures to subjects as part of a study examining the implications of chemotherapy and genetic risk factors on brain development in leukemia survivors Conducted computer scoring of psychological tests Scored questionnaires that apply measures pertaining to anxiety, emotions and self concept Attended biweekly lab meetings to analyze trends in subject assessment scores and behaviours. Appraised and presented related research to the principal investigator (PI) Stored, organized, and maintained patient data using Excel-based programming, while exhibiting careful attention to accuracy and completeness of results Trained incoming volunteers in study protocols, including computer scoring of cognitive tests, administering questionnaires, and storing confidential patient data

University of Toronto Global Brigades (UTGB) is U of T's chapter of the world's largest student-led international relief and non-profit organization, Global Brigades. UTGB sends both students and professionals alike to developing countries in an effort to improve the quality of life in rural communities. The mission is to improve health, water, sanitation, and economic infrastructures by providing rural communities with sustainable solutions under a holistic service model. Responsibilities: Coordinated executive team efforts to plan international medical, dental, and public health brigades that assisted under-resourced communities in Honduras Planned and executed fundraising events for brigades, local charities, and group operations, which typically saw 60-70 attendees and generated up to $500 in revenue Strategically marketed brigades to health professionals and students. Worked with Chair of Graphic Design to design promotional materials for recruiting and fundraising events Communicated our parent organization policies to the chapter. Created streamlined Excel documents for tracking group metrics over time. Critically analyzed data and developed insights into team operations, strategically addressing areas of weakness with teammates Worked cross-functionally with U of T Organization of Latin American Students (OLAS) to raise capital and create Spanish lessons for volunteers in preparation for brigades During my term as Vice President, health care and health education were provided to over 2000 patients in rural Honduran communities Personally attended two Medical/Dental Brigades in Honduras in 2013 and 2014

Planned and executed an individual research project in human biology within a seven-week timeframe Project topic involved researching the effects of cell starvation on mitochondrial morphology and overall cell activity Was trained in lab safety and aseptic technique, pipetting, eukaryotic/prokaryotic cell culturing, DNA amplification, plasmid transformation, protein expression, fluorescent tagging, preparing slides, gel electrophoresis Learned the required laboratory skills through self-study and communicating with Taiwanese lab students Performed extensive research, generated hypotheses, devised experiments, and critically analyzed experimental data to complete the project in a prompt and effective manner Attended weekly lab meetings with fellow students to share and analyze preliminary data through formal presentations. Identified experimental weaknesses and strategies to improve individual projects Presented project findings through a 45-minute PowerPoint presentation to over 50 students and a panel of four professors. Awarded an A+ for confident and engaging presentation style Wrote a ten-page scientific manuscript explaining and discussing the thesis, methods and results of the research project, which also garnered an A+