Camille Le Guilcher
Senior scientist discovery research @ Adcytherix
France
Paris
Pharmaceuticals
Physiopathologie, Oncologie, Édition de gènes, Thérapie génique, Virologie, Biomatériaux, Biologie moléculaire, Immuno-oncologie, Recherche en oncologie, Gestion d’équipe, Analyse des données, Travail d’équipe, Expérimentation Animal , Sens de l’organisation, Synthèse, Gestion des communications, Diffusion de la science, Compétences de coordination, Communication externe, Niveau élevé de précision
Experience

R&D Postdoctoral Researcher at INSERM U 1148
Région de Paris, France
R.H.U Innovations for Liver Tissue Engineering project: Development and preclinical study management of engineered human liver Publications: - Development of 3D hepatic constructs within polysaccharide-based scaffolds with tunable properties (IJMS, 2020) - Interplay between crosslinking and ice nucleation controls the porous structure of freeze-dried hydrogel (Biomater Adv, 2022) - Engineered human liver based on pullulan-dextran hydrogel promotes mice survival after liver failure (Mater Today Bio, 2023) - Fibroblasts mediate endothelium response to angiogenic cues in a newly developed 3D stroma engineered model (Biomater Adv, 2023)

PhD student at INSERM U1174
Orsay
Identification and preclinical study of therapeutic targets in liver diseases (liver failure, fibrosis, cirrhosis, NASH) Publication : The P2X4 purinergic receptor regulates hepatic myofibroblast activation during liver fibrogenesis (J Hepatol, 2018) Characterization of a drug candidate that targets T cell activation. Publication : Synthesis and characterization of store-operated calcium entry inhibitors active in the submicromolar range (IJMS, 2020) Patent : Inhibiteurs de l'entrée capacitive du calcium / Inventor member FR3097738, 2021

Stagiaire
INSERM U757
Orsay 91
Étude du rôle du récepteur P2X7 dans l’inflammation et la lésion au cours d’un modèle d’intoxication hépatique au tétrachlorure de carbone
Education
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