Bohong Zhang
Senior Director of CNS/Neuromuscular Disorders - Gene Editing @ Mammoth Biosciences
About
An accomplished and highly skilled leader with a long history of success guiding research and development teams in the pharmaceutical and biotech industries. Innovative problem solver who leverages extensive industry and technical knowledge to drive continuous improvement and conduct studies. Exceptional communication, cross-functional collaboration, and project management skills.
United States
Brisbane
Biotechnology
Molecular Biology, Rare Diseases, Creativity and Innovation, Protein Characterization, Pharmacology, Strategic Alliances, Biotherapeutics, Product Development, Gene Therapy, Strategic Partnerships, Protein Chemistry, Protein Purification, Biotechnology, Drug Discovery, Lifesciences, Purification, Biochemistry, Assay Development, Chromatography, Cell Culture
Experience
Senior Director of CNS/Neuromuscular Disorders - Gene Editing
Mammoth Biosciences
Brisbane, California, United States
Sr. Director, External Sciences Head
Takeda
Cambridge, Massachusetts
Oversaw external partnerships to bring new assets and innovation to the gene therapy pipeline. Guided the team to make scientific decisions to meet business goals in a timely manner and within budgets. Led cross-functional team in risk identification and management.
Sr. Director, Discovery Therapeutics
Shire
Managed a group of ten PhD scientists in the design and development of biotherapeutics for lysosomal deficiency and genetic diseases.
Director, Analytical Protein Chemistry / Biomolecular Research and Technologies
Shire HGT
Managed a group of six scientists in the biochemical and biophysical characterization of recombinant proteins and antibody drugs. Led the in vitro assay development, characterization of post-translational modification, protein formulation and CMC development.
Associate Director, Analytical Protein Chemistry / Biomolecular Research and Technologies
Shire HGT
Managed a group of six scientists in the biochemical and biophysical characterization of recombinant proteins and antibody drugs. Led the in vitro assay development, characterization of post-translational modification, protein formulation and CMC development.
Principal Research Specialist / Protein Expression & Purification Research
Shire HGT
Conducted studies of over 30 recombinant proteins for enzyme replacement therapy of lysosomal storage diseases and urea cycle disorders. Led the development of M6P-independent endocytosis for the treatment of MPS IIIB and successful demonstration of preclinical efficacy.
Sr. Research Specialist / Therapeutics
Transkaryotic Therapies, Inc
Cambridge, MA
Optimized mammalian transcriptional and translational elements to increase human FVIII expression up to 10-fold in ex vivo gene therapy for hemophilia A.
Education
Peking Union Medical College
Northeastern University
Regulatory Affairs
Peking University
Pre-Medicine/Pre-Medical Studies
Harvard Extension School
Bohong Zhang's Contact Information
Phone
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