Binbin Kou

Responsible for peptide drug design of treating metabolic disease and establishing peptide discovery platform for multiple disease area.

focus on peptide therapeutics in the field of metabolic disease, oncology and autoimmune disease

Focused overall 17 years research interest and 10 years in bio-tech and pharmaceutical industry experience in medicinal chemistry to find the lead compounds in chronic endocrine diseases, diabetes, obesity, cardiovascular disease, NASH and related targets. Extensive experience in peptide hormone lead compounds optimization by medicinal chemistry strategy and specializing in diabetes and obesity biology and pharmacology. Expertise and experience on designing, evaluating and optimizing macromolecular biologics oral bioavailability. Three-year experience on rare endocrine disease medication design, target validation, development and related emerging biotechnologies. Inventing prodrug chemistry platform of optimizing macromolecular drug delivery for enhanced pharmacokinetic and pharmacodynamic properties. Comprehensive expertise in peptide and small organic molecules synthesis, purification, characterization, analysis of chemical library and corresponding bio-assay. Sufficient knowledge on protein drug modalities biosynthesis, selective modification and purification.

I was trying to develop the new generation insulin by applying the prodrug strategy.