Andrew Buchanan FRSC

Senior Vice President: Head of Discovery

About

💉A discovery & innovations leader covering the target selection to first time in human (FiH) space. Experienced in oncology, inflammation, and cardiovascular therapy areas. Contributing to and leading teams delivering 20 FiH IND Biologics (IgG, peptides, ADC, bispecifics) of which 3, to date, made BLA and launch. 💬External R&D advisor for several private and public entities. ✝️ as a Christian I’m always interested in generous discussion and dialogue at the interfaces of natural science, AI, and faith. 🎖️Awards: 2022 AstraZeneca Oncology patent of the year 2021 AstraZeneca CEO award: Augmented Drug Design, leveraging data and AI 2020 AstraZeneca Science Star: tissue targeting (kidneys) 2020 Fellow Royal Society of Chemistry 2015 MedImmune Global Medicines Development award (Bentracimab) 2013 MedImmune CEO award: peptide innovation (GLP-1 related) 2005 UK Top Young British Scientists Commendation Award at House of Commons (work on Tralokinumab) 🛤️ pipeline track record: Looked back to see how many projects had I contributed to between 2001-2021. I was surprised. >50 Target selection to LO projects delivering Drug Candidate, which progressed to 20 INDs, 3 BLAs, including Imfinzi (PD-L1), Adbry (IL-13), and 40+ patents and original papers.

Country

United Kingdom

City

Cambridge

Industry

Biotechnology

Skill

Matrix Leadership, Clinical Research, Interdisciplinary Collaboration, Problem Solving, Community Outreach, Strategic Thinking, Defining Requirements, Performance Motivation, Complex Project Management, Join the dots, Faith, Targeted Drug Delivery, Artificial Intelligence (AI), Pharmacology, Creativity and Innovation, BPD, Candidate Selection, Antibody Engineering, Digital Strategy, People Development

Experience

Senior Vice President: Head of Discovery

Biotech in Stealth mode

2026-2 - Present · 8 mos

Vice President R&D

Biotech in Stealth mode

2025-5 - 2026-1 · 9 mos

Principal Scientist: Biologics Engineering

AstraZeneca

2022-10 - 2025-5 · 2 yrs 8 mos

Cambridgeshire, England, United Kingdom

🛜Innovation; chairing AZ Oncology Postdoc committee, initiating internal and external cross disciplinary collaborations 🎯Targeting: for ADC and RC pipeline 🎬Early career: Biologics education (academic & commercial) and mentorship

Off sick due to Mental Health

AstraZeneca

2021-6 - 2022-9 · 1 yr 4 mos

Cambridge, England, United Kingdom

Now restored and reformed with a renewed passion for partnership and enabling early career colleagues .

Senior Director: Biologics AI/ML strategy | CVRM pipeline

AstraZeneca

2021-1 - 2022-6 · 1 yr 6 mos

Cambridge, England, United Kingdom

Multidisciplinary direct line and matrixed global team leader. Responsibility include early CVRM Research Board and portfolio, Targeting tech, Peptide tech & Augmented Drug Design strategy and delivery

Director: Biologics AI/ML strategy | CVRM pipeline

MedImmune

2015 - 2020 · 5 yrs

Cambridge, United Kingdom

Antibody Discovery and Protein Engineering Augmented Biologics Drug Discovery (2016-2020) Project leadership in R&D Focus on diabetes, obesity, cardiovascular Responsibility for multidisciplinary global team leadership.