Andrea Pappas, Ph.D.
Director, Nonclinical Development @ Kriya Therapeutics, Inc.
About
Experienced biotech professional with a strong background in IND-enabling strategy, program management, and nonclinical development for gene therapy and vaccine programs. Skilled in pharmacology and toxicology, with interests in neuroscience, metabolic disease, molecular pharmacology, genetics, and gene regulation. Known for scientific rigor, strategic leadership, cross-functional collaboration, and the ability to align research with regulatory and corporate goals.
United States
Durham
Biotechnology
Molecular Neuroscience, Confocal Microscopy, PCR, Western Blotting, Molecular Biology, Genetics, Neuroscience, Molecular Cloning, Fluorescence Microscopy, Microscopy, Cell Culture, Biochemistry, Immunohistochemistry, Cell Biology, Animal Models, Tissue Culture, Transfection
Experience

Graduate Research Fellow
Durham, North Carolina
Graduate Research in the Laboratory of Yong-hui Jiang, M.D., Ph.D. • Generated a genetically altered mouse line that mimics mutations found in autism patients and discovered autistic behaviors, abnormal protein function and altered synapse transmission in the mice caused by the gene disruption. • Discovered novel protein regulatory mechanisms for the protein that when disrupted causes autism. − These discoveries will enable pharmaceutical testing for the future treatment of autism patients. • Demonstrated leadership and management skills while collaborating with 5 interdisciplinary laboratories at Duke University and University of North Carolina in order to accomplish the analysis of the mutant mouse line.

Undergraduate Research Assistant
Salt Lake City, Utah
Undergraduate Research Assistant in the laboratory of Erik Jorgensen, Ph.D. • Studied the molecular basis of synaptic transmission, focusing on the mechanisms of synaptic vesicle fusion. Discovered a novel protein that regulates G protein-coupled receptors (GPCRs) using a genetic screen for molecules involved in dense-core vesicle function in C. elegans.

Undergraduate Research Assistant
Salt Lake City, Utah
Undergraduate Research Assistant in the laboratory of Bonnie Punske, Ph.D. • Found delayed electrical propagation and recovery in insulin receptor deficient mouse hearts which model human diabetic hearts. This work elucidates reasons for increased risk of heart attacks in patients with diabetes.
Andrea Pappas, Ph.D.'s Contact Information
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