alka khanna

senior research scientist

About

Senior research scientist in drug discovery to bring innovative medicines to the market by utilizing my skills and knowledge base in areas of Drug metabolism & pharmacokinetics, Biotechnology & bioinformatics

Country

india

City

gurgaon

Industry

research

Skill

drug discovery, medicinal chemistry, pharmacology, biochemistry, life sciences, in vivo, in vitro, cell culture, drug design, molecular biology, hplc, biotechnology, high performance liquid chromatography, cell, assay development, protein expression, pharmaceutical industry, lc ms, lifesciences, pharmacokinetics, cell biology, drug metabolism

Experience

senior research scientist

daiich sankyo india pharma

2010-7 - 2017-1 · 6 yrs 7 mos

Established in vitro and in vivo DMPK labs. Standardized various in vitro ADME assays and screened compounds in these assays using LC-MS/MS quantification method. Managed in vivo labs for conducting PK, metabolite identification, mass balance, drug-drug interaction and transporter studies using LC-MS/MS analysis method. Performed PK/PD (Pharmacodynamics) analysis, toxicity dose calculation and human dose calculation of eight projects in infectious and inflammation therapeutic area.

senior research scientist

ranbaxy

1998-1 - 2010-1 · 12 yrs 1 mo

Established Biotechnology, Real time PCR and FACS labs. Developed cell based assays, recombinant cell lines expressing human genes in bacterial, baculovirus, mammalian and yeast expression system for screening of new chemical entities and herbal extracts Worked for GSK (Glaxo Smithkline) alliance project, currently molecule in Phase-1 clinical trial. First one to publish extended drug resistence of M.tuberculosis in India. Won Certificate of Appreciation, Team excellence Award in 2008 & 2009 Represented Ranbaxy in Biotech India Exhibition at New Delhi, India & Won first Prize Presented posters at national and international conferences Published research work in international journals