Aastha Kapoor, Ph.D., Post-Doc

Manager Clinical Sciences @ Johnson & Johnson Innovative Medicine

About

I’m Aastha Kapoor, a Manager in Clinical Sciences at Johnson & Johnson Innovative Medicine. My work centers on supporting late-stage clinical development by turning complex datasets into evidence that teams can confidently act on – through rigorous data review, analysis, and interpretation across ~200 patients and cross-functional collaboration for FDA and global submissions. I’m proud to help teams deliver on aggressive timelines, including a protocol amendment completed in 17 days and CCO-to-DBL in three weeks leading to submission. Breakthrough Designation (BTD) granted from the FDA for the head and neck cancer therapy. Beyond study support, I serve as a Data4You platform SME, creating practical learning resources and recorded trainings for 50+ clinical scientists to promote best practices, consistency, and faster onboarding. Also, leading the efforts for Artificial Intelligence (AI) based RECIST medical review. Earlier in my career, I worked in Discovery Research at J&J, leading efforts to improve the toxicity profile of a bispecific antibody in a prostate cancer Phase 1/2 program and developing a 3D tumor spheroid assay adopted by 100+ bench scientists. My training includes postdoctoral work at Thomas Jefferson University’s Sidney Kimmel Cancer Center and a PhD from IIT Bombay. I enjoy connecting with others across research and industry – especially those interested in oncology, translational science, and clinical development.

Country

United States

City

Philadelphia

Industry

Pharmaceuticals

Skill

Molecular Biology, PCR, Biotechnology, SDS-PAGE, Protein Purification, Cell Culture, Gel Electrophoresis, Biochemistry, Western Blotting, ELISA, Polymerase Chain Reaction (PCR), Grant Writing, Mouse Models, Confocal Microscopy, Cell Signaling, Extracellular Matrix, Cancer Biology, Angiogenesis, Research

Experience

Manager Clinical Sciences

Johnson & Johnson Innovative Medicine

2025-4 - Present · 1 yr 6 mos

United States

Senior Scientist Clinical Sciences

Johnson & Johnson Innovative Medicine

2023-5 - 2025-4 · 2 yrs

Spring House, Pennsylvania, USA

Second to the lead in conducting Phase 1/2 clinical trial with 200 patients - analyzing safety and efficacy data and working towards a submission to the FDA. Breakthrough Designation (BTD) granted by the FDA for the head and neck cancer therapy. Subject matter expert of 'Data4You' software - used for clinical data analysis. Conducting recorded meetings for a wide training group >50 clinical scientists.

Discovery Scientist

Johnson & Johnson Innovative Medicine

2021-12 - 2023-6 · 1 yr 7 mos

Spring House Pennsylvania USA

Therapeutic Area Lead for improving the toxicity profile of bispecific antibody that was in a Ph1/2 prostate cancer clinical trial. Developed 'spheroid assay' for the research and development unit (which comprises over 100 bench scientists) - a platform that mimics solid tumors and is being successfully used across the R&D unit to test anti-cancer drugs.

Biological Scientist

Johnson & Johnson Innovative Medicine

2021-2 - 2021-12 · 11 mos

Spring House, Pennsylvania, USA

Post Doctoral Fellow, Sidney Kimmel Cancer Center

Thomas Jefferson University

2017-4 - 2021-2 · 3 yrs 11 mos

Philadelphia, Pennsylvania, United States

Studied the anti-angiogenic properties of 'Endorepellin. Generated genetically modified mouse models to study the mechanism of action of Endorepellin. Developed the 'aortic ring assay' to test 2 anti-angiogenic molecules. Actively collaborated on 2 projects outside the laboratory and published papers. Trained and mentored 2 graduate students and 1 visiting scholar.

Vice President, Jefferson Postdoctoral Association

Thomas Jefferson University

2018-6 - 2019-7 · 1 yr 2 mos

Coordinated a team of 8 members (Social Affairs lead, Election Nominations lead, Treasurers, and Secretary) to host the postdoctoral research symposium (PRS). Improved overall industry-academia interaction (by 15%) through career fairs and industry showcases. Boosted participation of postdocs (by 25%) in technical skills seminars (TSS) by awarding certificates. Chair for career roundtable session.

Graduate Student

Indian Institute of Technology, Bombay

2010-12 - 2016-10 · 5 yrs 11 mos

Mumbai Area, India

Junior Research Fellowship (JRF) by UGC, India for Ph.D. at IIT Bombay. Developed cisplatin and paclitaxel chemoresistant ovarian cancer cells for studying cancer invasion and metastasis. Collaborated with Tata Hospital to study the resistance caused by radiotherapy. Mentored 2 undergraduate students. Overcame a resource deficiency: collaborated with a forensic lab to perform cell line authentication - reducing the authentication costs by 50%.